{"title":"A look into the future: Your biological sex may guide chronic pain treatment.","authors":"Marzia Malcangio, George Sideris-Lampretsas","doi":"10.1016/j.neuron.2025.02.008","DOIUrl":null,"url":null,"abstract":"<p><p>Neuropathic pain constitutes a clinical problem more prevalent among women. In this issue of Neuron, Fan et al.<sup>1</sup> identify distinct sex-dependent pathways driving nociception. Importantly, T cells release the adipokine leptin in female but not male rodents, offering a novel approach for pain relief in women.</p>","PeriodicalId":19313,"journal":{"name":"Neuron","volume":"113 6","pages":"800-802"},"PeriodicalIF":15.0000,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Neuron","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.neuron.2025.02.008","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"NEUROSCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
Neuropathic pain constitutes a clinical problem more prevalent among women. In this issue of Neuron, Fan et al.1 identify distinct sex-dependent pathways driving nociception. Importantly, T cells release the adipokine leptin in female but not male rodents, offering a novel approach for pain relief in women.
期刊介绍：
Established as a highly influential journal in neuroscience, Neuron is widely relied upon in the field. The editors adopt interdisciplinary strategies, integrating biophysical, cellular, developmental, and molecular approaches alongside a systems approach to sensory, motor, and higher-order cognitive functions. Serving as a premier intellectual forum, Neuron holds a prominent position in the entire neuroscience community.
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