A prospective multicenter non-inferiority trial to evaluate a new burn rehabilitation program based on the International Classification of Functioning, Disability and Health (ICF)
Leila Harhaus , Hans Ziegenthaler , Hubert Neubauer , Felix J. Klimitz , Mareike Strupat , Sabine Ripper , Ulrich Kneser , Annette Stolle
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Abstract
Background
Burn injuries have a lasting impact on physical and psychological health. This study evaluated outcomes for two burn-specific rehabilitation programs based on the International Classification of Functioning, Disability, and Health (ICF) model.
Methods
In a prospective multicenter trial, 103 patients with work-related burn injuries underwent multidisciplinary rehabilitation in either a newly established ICF-based program (Center A) or a well-established program (Center B). A comprehensive outcome assessment was performed at the beginning (T1) and the end of inpatient rehabilitation (T2), and at three (T3) and 12 months (T4) after discharge to evaluate the effectiveness of the two rehabilitation programs. The study included an analysis of longitudinal changes within each center to assess patient outcomes over time and a comparison between the two centers at each time point to evaluate potential differences in rehabilitation effectiveness. Primary outcomes were the Physical Component Score (PCS) and Mental Component Score (MCS) of the 36-Item Short Form Survey (SF-36), with secondary outcomes including grip strength, active range of motion (AROM), and burn scar assessment among others.
Results
Results showed significant improvements in physical health (SF-36 PCS) from T1 to T4 (p < 0.001), while mental health (SF-36 MCS) showed no significant change (p = 0.20). Grip strength and AROM improved significantly over time in both centers. Non-inferiority between centers was confirmed for all outcomes except MCS at T2 and T3.
Conclusion
This study highlights the positive impact of ICF-based rehabilitation on physical recovery, with ongoing mental health needs underscoring the importance of long-term psychological support for burn survivors.
期刊介绍：
Burns aims to foster the exchange of information among all engaged in preventing and treating the effects of burns. The journal focuses on clinical, scientific and social aspects of these injuries and covers the prevention of the injury, the epidemiology of such injuries and all aspects of treatment including development of new techniques and technologies and verification of existing ones. Regular features include clinical and scientific papers, state of the art reviews and descriptions of burn-care in practice.
Topics covered by Burns include: the effects of smoke on man and animals, their tissues and cells; the responses to and treatment of patients and animals with chemical injuries to the skin; the biological and clinical effects of cold injuries; surgical techniques which are, or may be relevant to the treatment of burned patients during the acute or reconstructive phase following injury; well controlled laboratory studies of the effectiveness of anti-microbial agents on infection and new materials on scarring and healing; inflammatory responses to injury, effectiveness of related agents and other compounds used to modify the physiological and cellular responses to the injury; experimental studies of burns and the outcome of burn wound healing; regenerative medicine concerning the skin.
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