UK Hand and Upper Limb Transplant Service, functional outcomes of the first six patients: A case series.

IF 1.6 The Journal of hand surgery, European volume Pub Date : 2025-09-01 Epub Date: 2025-03-22 DOI:10.1177/17531934251325654
Joanna Burdon, Sarah Taplin, David A Leonard, Ibrahim Natalwala, Grainne Bourke, Simon P Kay
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Abstract

To date, three unilateral and seven bilateral hand and upper limb transplants have been performed by the UK Hand Transplant Programme. We report functional outcomes for our first six patients, who have been followed for between 4 and 10 years. All patients gained protective sensation to pain, pressure and temperature, and a recordable power grip. All patients saw an improvement in the Canadian Occupational Performance Measure performance and satisfaction scores, with five out of six patients improving the Disability of the Arm Shoulder and Hand scores. The Hand Transplant Score System graded all distal transplants as either a 'good' or 'excellent' with proximal transplants scoring 'fair' or 'good'. Hand transplant is an effective treatment in selected patients with continual improvements in function seen for up to 5 years.Level of evidence: IV.

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英国手部和上肢移植服务,前6名患者的功能结局:一个病例系列。
迄今为止,英国手部移植计划已经实施了3例单侧和7例双侧手部和上肢移植手术。我们报告了前6名患者的功能结果,他们被随访了4到10年。所有患者均获得疼痛、压力和温度的保护感觉,并获得可记录的握力。所有患者在加拿大职业表现测量中的表现和满意度得分都有所改善,6名患者中有5名改善了手臂、肩膀和手的残疾得分。手部移植评分系统将所有远端移植分为“良好”或“优秀”,近端移植分为“一般”或“良好”。手部移植是一种有效的治疗方法,可以持续改善患者的功能长达5年。证据等级:四级。
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