Clear cell sarcoma of salivary gland: A case report

IF 0.2 Q4 ONCOLOGY Current problems in cancer. Case reports Pub Date : 2025-06-01 Epub Date: 2025-03-17 DOI:10.1016/j.cpccr.2025.100359
Saša Z. Tabaković , Sonja Tabaković
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Abstract

Introduction

Malignant mesenchymal tumors of the salivary glands are neoplasms whose histopathological picture represents a very big diagnostic challenge. Most tumors of the parotid glands are benign, and for malignant neoplasms, immunohistochemistry is essential for diagnosis.

Aim

The aim is to present a rare case of a mesenchymal malignant tumor of the parotid gland, including diagnostics and surgical therapy.

Case presentation

A 67-year-old patient presented with a tumor around the parotid gland. Sonographically, the change resembled an adenoma, although the differential diagnosis did not exclude a pathological entity of another etiology. The patient underwent a superficial parotidectomy, and the operative and postoperative course was without complications. Immunohistochemical analysis in combine with histopath results confirmed the final diagnosis of Clear Cell Sarcoma of the parotid gland.

Conclusion

Clear cell sarcoma of the parotid gland is a rare malignant neoplasm. Timely diagnosis and total parotidectomy with negative resection margins, in the first year after the operation ensure a satisfactory postoperative result without recurrence and meta-changes. Doctors should be very cautious in such situations because the histopathological examination with immunohistochemical analysis gives a clear picture of the tumor in question as a differential diagnosis.
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唾液腺透明细胞肉瘤1例
唾液腺恶性间充质瘤是一种组织病理学图像对诊断具有很大挑战的肿瘤。大多数腮腺肿瘤是良性的,对于恶性肿瘤,免疫组织化学是诊断的必要条件。目的报告一例罕见的腮腺间充质恶性肿瘤,包括诊断和手术治疗。病例介绍:一位67岁的患者,在腮腺周围发现肿瘤。超声检查,改变类似于腺瘤,虽然鉴别诊断不能排除其他病因的病理实体。患者行腮腺浅表切除术,手术及术后无并发症。免疫组化分析结合组织病理学结果证实了腮腺透明细胞肉瘤的最终诊断。结论腮腺透明细胞肉瘤是一种罕见的恶性肿瘤。术后一年内及时诊断并行阴性切缘全腮腺切除术,可确保术后无复发及meta改变。在这种情况下,医生应该非常谨慎,因为组织病理学检查和免疫组织化学分析提供了肿瘤的清晰图像,作为鉴别诊断。
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CiteScore
0.40
自引率
0.00%
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0
审稿时长
96 days
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