MIP-based sensing strategies for the diagnosis of prostate and lung cancers

Abstract

Prostate and lung cancer are among the most prevalent and lethal forms of the disease, and, globally, cancer is a primary cause of mortality. Early diagnosis and the application of precise biomarkers are crucial for prolonging patient lifespan and enhancing quality of life. Molecularly imprinted polymers (MIPs) are synthetic substances capable of selectively identifying and binding specific target molecules. Besides their sensitivity to biomolecules, MIPs offer significant advantages in cancer biomarker detection due to their cost-effectiveness and flexible architectures. MIP-based biosensors designed for the detection of prostate and lung cancer-specific biomarkers provide unique solutions that enhance the diagnostic process and improve its accuracy. This study aims to assess the present state of MIP-based biosensors in the detection of biomarkers for prostate and lung cancer, as well as the potential opportunities provided by this technology. This study will present an overview of potential biomarkers for lung and prostate cancer, clarify the fundamental features of MIPs, and discuss their uses in MIP-based biosensors along with prospective future applications. In this context, our review is aimed to contribute to the development of innovative methods used in early cancer diagnosis.