Quality of Life Status and Its Influencing Factors Among Lung Cancer Chemotherapy Patients in China: A Cross-Sectional Study.

IF 2.6 4区 医学 Q3 ONCOLOGY Cancer Management and Research Pub Date : 2025-03-17 eCollection Date: 2025-01-01 DOI:10.2147/CMAR.S510811
Fan Xu, Xiaoli Zhong, Qiao Li, Xi Luo, Na Wang, Jing Wang, Shaoju Xie, Jiquan Zhang
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Abstract

Background: Improving the quality of life (QOL) of lung cancer patients undergoing chemotherapy is an indispensable part of cancer treatment, as it not only pertains to their physical health but also to their psychological and social well-being. Previous research has primarily focused on investigating health-related quality of life, while studies specifically addressing the QOL of lung cancer patients remain underrepresented and under researched.

Purpose: The study aims to investigate the current status of QOL among lung cancer patients and identify the predictive factors associated with QOL.

Patients and methods: From January 2024 to June 2024, lung cancer patients undergoing chemotherapy will be recruited from the outpatient clinics or wards of a tertiary A-level hospital in Deyang City as research subjects. They will be surveyed using the general information questionnaire, the Self-rating Depression Scale (SDS), the Multidimensional Scale of Perceived Social Support (MSPSS), and the Functional Assessment of Cancer Therapy-Lung (FACT-L) scale. Multiple linear regression analysis will be employed to determine the variables associated with QOL.

Results: A total of 390 lung cancer patients undergoing chemotherapy were recruited for this study, with a male predominance accounting for 72.31%. The mean age was (59.11±11.37) years. The overall QOL score was (66.43±23.67). Age, family monthly income per capita, cancer clinical stage, depression, and perceived social support (PSS) were identified as independent factors influencing the QOL of lung cancer patients, accounting for 19.4% of the total variance.

Conclusion: There is still considerable room for improvement in the overall QOL of lung cancer patients undergoing chemotherapy. Based on the analysis of influencing factors, targeted and personalized intervention measures should be implemented to enhance the QOL for these patients.

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中国肺癌化疗患者生活质量状况及其影响因素的横断面研究
背景:提高肺癌化疗患者的生活质量(QOL)是癌症治疗不可缺少的一部分,不仅关系到患者的身体健康,也关系到患者的心理和社会健康。以前的研究主要集中在调查与健康相关的生活质量,而专门针对肺癌患者生活质量的研究仍然代表性不足,研究不足。目的:了解肺癌患者生活质量的现状,探讨影响生活质量的相关预测因素。患者与方法:2024年1月至2024年6月,在德阳市某三级甲等医院门诊或病房内招募肺癌化疗患者作为研究对象。他们将使用一般信息问卷、抑郁自评量表(SDS)、感知社会支持多维量表(MSPSS)和癌症治疗-肺功能评估量表(FACT-L)进行调查。多元线性回归分析将用于确定与生活质量相关的变量。结果:本研究共纳入390例接受化疗的肺癌患者,男性占72.31%。平均年龄(59.11±11.37)岁。总体生活质量评分为(66.43±23.67)分。年龄、家庭人均月收入、癌症临床分期、抑郁、感知社会支持(PSS)是影响肺癌患者生活质量的独立因素,占总方差的19.4%。结论:肺癌化疗患者的总体生活质量仍有较大的提高空间。在分析影响因素的基础上,实施针对性、个性化的干预措施,提高患者的生活质量。
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来源期刊
Cancer Management and Research
Cancer Management and Research Medicine-Oncology
CiteScore
7.40
自引率
0.00%
发文量
448
审稿时长
16 weeks
期刊介绍: Cancer Management and Research is an international, peer reviewed, open access journal focusing on cancer research and the optimal use of preventative and integrated treatment interventions to achieve improved outcomes, enhanced survival, and quality of life for cancer patients. Specific topics covered in the journal include: ◦Epidemiology, detection and screening ◦Cellular research and biomarkers ◦Identification of biotargets and agents with novel mechanisms of action ◦Optimal clinical use of existing anticancer agents, including combination therapies ◦Radiation and surgery ◦Palliative care ◦Patient adherence, quality of life, satisfaction The journal welcomes submitted papers covering original research, basic science, clinical & epidemiological studies, reviews & evaluations, guidelines, expert opinion and commentary, and case series that shed novel insights on a disease or disease subtype.
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