Palliative Care Program Characteristics and End-of-Life Outcomes for Patients With Metastatic Cancer

IF 3.5 2区 医学 Q2 CLINICAL NEUROLOGY Journal of pain and symptom management Pub Date : 2025-06-01 Epub Date: 2025-03-22 DOI:10.1016/j.jpainsymman.2025.03.020
May Hua MD, MS , Ling Guo MD, MS , Shuang Wang PhD , R. Sean Morrison MD
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Abstract

Context

Although U.S. palliative care programs have substantial differences in their implementation, whether this heterogeneity impacts patient outcomes is unknown.

Objectives

To determine if palliative care program characteristics are associated with differences in end-of-life quality metrics for patients with metastatic cancer.

Methods

Retrospective cohort study of patients with metastatic cancer who received care from programs that participated in the National Palliative Care Registry, 2018–2019. Multilevel regression was used to examine the association between individual program characteristics and outcomes including use of hospice, hospice enrollment ≥ 3 days, use of intensive care (ICU) in the last 30 days of life, and use of chemotherapy in the last 14 days of life.

Results

The cohort was comprised of 33,015 patients who received care from 235 palliative care programs. Program maturity was the only characteristic associated with a difference in any outcome. Patients who received care from mature programs were more likely to use hospice (adjusted hazard ratio (aHR) 1.15 [1.06–1.25], for 5–10 years vs. < 5 years; aHR 1.18 [1.09–1.29] for > 10 years vs. < 5 years), and were also more likely to have hospice enrollment ≥ 3 days (aHR 1.18 [1.08–1.31] for 5–10 years vs. < 5 years; aHR 1.22 [1.11–1.34] for > 10 years vs.< 5 years).

Conclusion

Palliative care program characteristics largely were not associated with differences in end-of-life quality metrics for patients with metastatic cancer. Further work is needed to better understand why program maturity may be associated with improved outcomes.
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姑息治疗项目的特点与转移性癌症患者的临终结局。
背景:尽管美国姑息治疗项目在实施上存在实质性差异,但这种异质性是否会影响患者的预后尚不清楚。目的:确定姑息治疗方案的特点是否与转移性癌症患者临终质量指标的差异相关。方法:回顾性队列研究2018-2019年参与国家姑息治疗登记处项目的转移性癌症患者。采用多水平回归检验个体项目特征与结局之间的关系,包括安宁疗护的使用、安宁疗护登记≥3天、生命最后30天内的重症监护(ICU)使用,以及生命最后14天内的化疗使用。结果:该队列包括33,015名患者,他们接受了235个姑息治疗项目的治疗。规划成熟度是与任何结果的差异相关的唯一特征。接受成熟项目护理的患者更有可能使用安宁疗护(调整风险比(aHR) 1.15[1.06-1.25],持续5-10年vs < 5年;5 - 10年和< 5年的aHR分别为1.18[1.09-1.29]和1.18[1.08-1.31],且更有可能接受安宁疗护≥3天(5 - 10年和< 5年的aHR分别为1.18 [1.08-1.31]);10年对< 5年的aHR为1.22[1.11-1.34]。结论:姑息治疗方案的特点在很大程度上与转移性癌症患者临终质量指标的差异无关。需要进一步的工作来更好地理解为什么规划成熟度可能与改进的结果相关联。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
8.90
自引率
6.40%
发文量
821
审稿时长
26 days
期刊介绍: The Journal of Pain and Symptom Management is an internationally respected, peer-reviewed journal and serves an interdisciplinary audience of professionals by providing a forum for the publication of the latest clinical research and best practices related to the relief of illness burden among patients afflicted with serious or life-threatening illness.
期刊最新文献
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