Co-carriage of blaNDM-1 and blaVIM-2 in different plasmids of Acinetobacter junii isolate and the transfer of blaNDM-1-carrying plasmids to Gram-negative bacteria
Md Shohel Rana , Shukho Kim , Seo Yeon Ko , Nayeong Kim , Seong Yeob Kim , Da Eun Lee , Ki Tae Kwon , Yu Kyung Kim , Je Chul Lee
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Abstract
Carbapenem-resistant Acinetobacter junii isolate co-carried blaVIM-2 and blaNDM-1 in different plasmids. blaNDM-1- and blaVIM-2-carrying plasmids were characterized using the whole genome sequencing. The expression of blaNDM-1 was higher than that of blaVIM-2. blaNDM-1-carrying plasmid was conjugally transferred to various Gram-negative bacterial species. The transferability of blaNDM-1-carrying plasmid raises concerns about the potential spread of carbapenem resistance across diverse bacterial populations.
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Journal of Microbiology Immunology and Infection is an open access journal, committed to disseminating information on the latest trends and advances in microbiology, immunology, infectious diseases and parasitology. Article types considered include perspectives, review articles, original articles, brief reports and correspondence.
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