{"title":"A fatal case of pulmonary cryptococcosis in an apparently immunocompetent patient from Cote D′ Ivoire","authors":"Ahou Sandrine Konan , Kalou Dibert Zika , Affoué Sandrine Josette Kouakou , Appi Sandrine Kouamé , Malick Senanminfoun Soro , Koffi Daho Adoubryn","doi":"10.1016/j.mmcr.2025.100701","DOIUrl":null,"url":null,"abstract":"<div><div>Cryptococcosis is an opportunistic mycosis caused by <em>Cryptococcus</em>, mainly affecting the immunocompromised. We report a case of pulmonary cryptococcosis within a 31-year-old immunocompetent patient admitted for painful chest swelling evolving for 4 months prior to admission. The chest X-Ray showed a rounded pulmonary opacity. The chest ultrasound revealed a pulmonary abscess diffusing under the skin. Direct examination using the Indian ink and the May-Grunwald Giemsa staining revealed encapsulated yeasts in the pus. The Culture of the pus on the Sabouraud medium with chloramphenicol confirmed the presence of <em>Cryptococcus neoformans</em>. Cryptococcal antigen was positive. This case reminds us that cryptococcosis should be considered even without immunosuppression.</div></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"48 ","pages":"Article 100701"},"PeriodicalIF":1.3000,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medical Mycology Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2211753925000107","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}
引用次数: 0
Abstract
Cryptococcosis is an opportunistic mycosis caused by Cryptococcus, mainly affecting the immunocompromised. We report a case of pulmonary cryptococcosis within a 31-year-old immunocompetent patient admitted for painful chest swelling evolving for 4 months prior to admission. The chest X-Ray showed a rounded pulmonary opacity. The chest ultrasound revealed a pulmonary abscess diffusing under the skin. Direct examination using the Indian ink and the May-Grunwald Giemsa staining revealed encapsulated yeasts in the pus. The Culture of the pus on the Sabouraud medium with chloramphenicol confirmed the presence of Cryptococcus neoformans. Cryptococcal antigen was positive. This case reminds us that cryptococcosis should be considered even without immunosuppression.
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