{"title":"Interactome of the oncogenic ΔNp73α isoform in human papillomavirus 38 E6/E7-transformed keratinocytes.","authors":"Luc Negroni, Valerio Taverniti, Massimo Tommasino, Katia Zanier","doi":"10.1128/mra.01071-24","DOIUrl":null,"url":null,"abstract":"<p><p>ΔNp73α is a major oncogenic isoform of tumor suppressor p73. Here, we report ΔNp73α protein-binding partners in the organelle and cytoplasmic compartments of a cellular model consisting of human keratinocytes transformed by the E6 and E7 oncoproteins of the β-HPV38 virus associated with non-melanoma skin cancer.</p>","PeriodicalId":18654,"journal":{"name":"Microbiology Resource Announcements","volume":" ","pages":"e0107124"},"PeriodicalIF":0.7000,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11984131/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Microbiology Resource Announcements","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1128/mra.01071-24","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/3/26 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"MICROBIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
ΔNp73α is a major oncogenic isoform of tumor suppressor p73. Here, we report ΔNp73α protein-binding partners in the organelle and cytoplasmic compartments of a cellular model consisting of human keratinocytes transformed by the E6 and E7 oncoproteins of the β-HPV38 virus associated with non-melanoma skin cancer.
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