MXene-Based Electrochemical Biosensors: Advancing Detection Strategies for Biosensing (2020-2024).

IF 5.6 3区工程技术 Q1 CHEMISTRY, ANALYTICAL Biosensors-Basel Pub Date : 2025-02-20 DOI:10.3390/bios15030127

Joydip Sengupta, Chaudhery Mustansar Hussain

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Abstract

MXenes, a class of two-dimensional materials, have emerged as promising candidates for developing advanced electrochemical biosensors due to their exceptional electrical conductivity, large surface area, and rich surface chemistry. These unique properties enable high sensitivity, rapid response, and versatile functionalization, making MXene-based biosensors highly suitable for detecting biomolecules and pathogens in biomedical applications. This review explores recent advancements in MXene-based electrochemical biosensors from 2020 to 2024, focusing on their design principles, fabrication strategies, and integration with microfluidic platforms for enhanced performance. The potential of MXene sensors to achieve real-time and multiplexed detection is highlighted, alongside the associated challenges. Emphasis is placed on the role of MXenes in addressing critical needs in disease diagnostics, personalized medicine, and point-of-care testing, providing insights into future trends and transformative possibilities in the field of biomedical sensing technologies.

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基于mxene的电化学生物传感器：推进生物传感的检测策略（2020-2024）。

MXenes是一类二维材料，由于其优异的导电性、大表面积和丰富的表面化学性质，已成为开发先进电化学生物传感器的有希望的候选者。这些独特的特性使得高灵敏度、快速响应和多功能功能化，使得基于mxene的生物传感器非常适合在生物医学应用中检测生物分子和病原体。本文综述了从2020年到2024年基于mxene的电化学生物传感器的最新进展，重点介绍了它们的设计原理、制造策略以及与微流控平台的集成以提高性能。MXene传感器在实现实时和多路检测方面的潜力得到了强调，同时也面临相关挑战。重点是MXenes在解决疾病诊断、个性化医疗和护理点检测方面的关键需求方面的作用，提供对生物医学传感技术领域未来趋势和变革可能性的见解。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Biosensors-Basel Biochemistry, Genetics and Molecular Biology-Clinical Biochemistry

CiteScore

6.60

自引率

14.80%

发文量

983

审稿时长

11 weeks

期刊介绍： Biosensors (ISSN 2079-6374) provides an advanced forum for studies related to the science and technology of biosensors and biosensing. It publishes original research papers, comprehensive reviews and communications. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. There is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced. Electronic files and software regarding the full details of the calculation or experimental procedure, if unable to be published in a normal way, can be deposited as supplementary electronic material.