Analysis of the correlation between ABO blood type and three bone mineral density measurements in patients with lumbar degenerative diseases.

IF 2.7 3区 医学 Q2 CLINICAL NEUROLOGY European Spine Journal Pub Date : 2025-05-01 Epub Date: 2025-03-27 DOI:10.1007/s00586-025-08796-y
Yongdi Wang, Youwei Ai, Qian Chen, Juehan Wang, Hong Ding, Dun Luo, Zhuojie Xiao, Ce Zhu, Limin Liu
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Abstract

Purpose: The purpose of this study is to evaluate the association between ABO blood type and three bone mineral density (BMD) measurements including CT Hounsfield units (HU), vertebral bone quality (VBQ) scores, and Dual-energy x-ray absorptiometry (DEXA) in patients undergoing transforaminal lumbar interbody fusion (TLIF) for lumbar degenerative diseases (LDD) and determine the postoperative BMD-related complications and patient-reported outcomes in four ABO-type groups.

Methods: This study included patients undergoing single-level TLIF for LDD at our center from 2014 to 2020. Demographic and clinical information were collected. The correlation between ABO blood type and three BMD measurements was analyzed. Radiographic images, the visual analog scale (VAS) score of back and leg pain, and the Oswestry Disability Index (ODI) were used to compare the differences in BMD-related complications and patient-reported outcomes between four ABO-type groups.

Results: 350 patients were included in this study. ABO blood group distribution is O (33.7%), A (32.6%), B (24.6%), and AB (9.7%). The values of CT HU in four groups have a significant difference (P = 0.001). Patients with CT HU ≤ 110 were older (62.6 ± 11.6 vs. 58.4 ± 13.4, P = 0.022) and had a higher proportion of O blood type (45.2% vs. 31.3%) compared to patients with CT HU>110. There are no statistically significant differences in BMD-related complications and patient-reported outcomes between the four ABO-type groups.

Conclusion: Our study found a close connection between ABO blood type and CT HU in patients undergoing TLIF for LDD and determined O blood type is a risk factor for osteoporosis.

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腰椎退行性疾病患者ABO血型与三项骨密度指标的相关性分析。
目的:本研究的目的是评估ABO血型与三种骨密度(BMD)测量之间的关系,包括CT Hounsfield单位(HU)、椎体骨质量(VBQ)评分和双能x线骨密度测量(DEXA),这些测量包括经椎间孔腰椎椎体间融合术(TLIF)治疗腰椎退行性疾病(LDD)的患者,并确定四种ABO血型组的术后BMD相关并发症和患者报告的结果。方法:本研究纳入2014年至2020年在我中心接受单阶段TLIF治疗LDD的患者。收集了人口统计学和临床资料。分析ABO血型与三项BMD指标的相关性。采用影像学图像、视觉模拟评分(VAS)、背部和腿部疼痛评分以及Oswestry残疾指数(ODI)来比较4个abo型组之间bmd相关并发症和患者报告结局的差异。结果:本研究纳入了350例患者。ABO血型分布为O型(33.7%)、A型(32.6%)、B型(24.6%)、AB型(9.7%)。四组患者CT HU值差异有统计学意义(P = 0.001)。CT HU≤110的患者年龄较大(62.6±11.6∶58.4±13.4,P = 0.022), O型血比例较高(45.2%∶31.3%)。在四个abo型组之间,bmd相关并发症和患者报告的结果没有统计学上的显著差异。结论:本研究发现LDD TLIF患者ABO血型与CT HU有密切关系,确定O型血是骨质疏松的危险因素。
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来源期刊
European Spine Journal
European Spine Journal 医学-临床神经学
CiteScore
4.80
自引率
10.70%
发文量
373
审稿时长
2-4 weeks
期刊介绍: "European Spine Journal" is a publication founded in response to the increasing trend toward specialization in spinal surgery and spinal pathology in general. The Journal is devoted to all spine related disciplines, including functional and surgical anatomy of the spine, biomechanics and pathophysiology, diagnostic procedures, and neurology, surgery and outcomes. The aim of "European Spine Journal" is to support the further development of highly innovative spine treatments including but not restricted to surgery and to provide an integrated and balanced view of diagnostic, research and treatment procedures as well as outcomes that will enhance effective collaboration among specialists worldwide. The “European Spine Journal” also participates in education by means of videos, interactive meetings and the endorsement of educative efforts. Official publication of EUROSPINE, The Spine Society of Europe
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