Meta-analysis and mechanism review of WRKY transcription factors overexpression controlling fruit and vegetable diseases

IF 6.8 1区农林科学 Q1 AGRONOMY Postharvest Biology and Technology Pub Date : 2025-08-01 Epub Date: 2025-03-28 DOI:10.1016/j.postharvbio.2025.113538

Xiaodong Fu , Fujun Li , Xiaoan Li, Xinhua Zhang

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Abstract

Disease has always been a key factor limiting the development of fruit and vegetables and is difficult to overcome. Tryptophan-arginine-lysine-tyrosine (WRKY) transcription factors (TF) have been widely studied for their excellent role in controlling fruit and vegetable diseases. Through meta-analysis, this study reveals the role of WRKY TFs overexpression in regulating fruit and vegetable disease resistance and summarizes the underlying mechanisms of WRKY improving disease resistance by regulating the activity of disease resistant proteins, phenylpropanoid pathways, pattern-triggered immunity and effector-triggered immunity, reactive oxygen species metabolism, and hormone signal crosstalk. In addition, this study discusses the interaction between WRKY TFs and ncRNA, as well as their post-translational modifications, aiming to contribute to a comprehensive understanding of the complex defense function of WRKY during fruit and vegetable biotic stress and provide theoretical basis for establishing comprehensive strategies for controlling fruit and vegetable diseases.

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WRKY转录因子过表达调控果蔬病害的meta分析及机制综述

疾病一直是制约果蔬发展的关键因素，也是难以克服的。色氨酸-精氨酸-赖氨酸-酪氨酸（WRKY）转录因子因其在果蔬病害防治中的重要作用而受到广泛的研究。本研究通过meta分析揭示了WRKY TFs过表达在果蔬抗病性调控中的作用，总结了WRKY通过调控抗病蛋白活性、苯丙素通路、模式触发免疫和效应触发免疫、活性氧代谢和激素信号串扰等途径提高果蔬抗病性的潜在机制。此外，本研究还探讨了WRKY TFs与ncRNA的相互作用及其翻译后修饰，旨在全面了解WRKY在果蔬生物胁迫中的复杂防御功能，为制定综合防治果蔬病害的策略提供理论依据。

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来源期刊

Postharvest Biology and Technology 农林科学-农艺学

CiteScore

12.00

自引率

11.40%

发文量

309

审稿时长

38 days

期刊介绍： The journal is devoted exclusively to the publication of original papers, review articles and frontiers articles on biological and technological postharvest research. This includes the areas of postharvest storage, treatments and underpinning mechanisms, quality evaluation, packaging, handling and distribution of fresh horticultural crops including fruit, vegetables, flowers and nuts, but excluding grains, seeds and forages. Papers reporting novel insights from fundamental and interdisciplinary research will be particularly encouraged. These disciplines include systems biology, bioinformatics, entomology, plant physiology, plant pathology, (bio)chemistry, engineering, modelling, and technologies for nondestructive testing. Manuscripts on fresh food crops that will be further processed after postharvest storage, or on food processes beyond refrigeration, packaging and minimal processing will not be considered.