{"title":"Simulation study on the force-electric effect of piezoelectric bone and osteocytes under static and dynamic compression.","authors":"Zhu Wang, Haiying Liu, Hanqing Zhao, Chunqiu Zhang","doi":"10.1080/10255842.2025.2484562","DOIUrl":null,"url":null,"abstract":"<p><p>This study analyzed the generation rule of streaming potential (SP) considering the piezoelectric effect of bone under static and dynamic compression. The piezoelectric equation was introduced into the equation of SP, and an osteon's 3D fluid-structure interaction finite element model with osteocytes was developed using COMSOL software. Seven working conditions helped study SP. The results showed positive and negative SP alternately acted on osteocyte under dynamic loads, and SP was about three orders of magnitude higher than that under static loads. Therefore, dynamic loads improved the osteocytes' force-electric microenvironment. The force-electric effect revealed the mechanism of treatment of osteoporosis.</p>","PeriodicalId":50640,"journal":{"name":"Computer Methods in Biomechanics and Biomedical Engineering","volume":" ","pages":"1-11"},"PeriodicalIF":1.6000,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Computer Methods in Biomechanics and Biomedical Engineering","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1080/10255842.2025.2484562","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS","Score":null,"Total":0}
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Abstract
This study analyzed the generation rule of streaming potential (SP) considering the piezoelectric effect of bone under static and dynamic compression. The piezoelectric equation was introduced into the equation of SP, and an osteon's 3D fluid-structure interaction finite element model with osteocytes was developed using COMSOL software. Seven working conditions helped study SP. The results showed positive and negative SP alternately acted on osteocyte under dynamic loads, and SP was about three orders of magnitude higher than that under static loads. Therefore, dynamic loads improved the osteocytes' force-electric microenvironment. The force-electric effect revealed the mechanism of treatment of osteoporosis.
期刊介绍：
The primary aims of Computer Methods in Biomechanics and Biomedical Engineering are to provide a means of communicating the advances being made in the areas of biomechanics and biomedical engineering and to stimulate interest in the continually emerging computer based technologies which are being applied in these multidisciplinary subjects. Computer Methods in Biomechanics and Biomedical Engineering will also provide a focus for the importance of integrating the disciplines of engineering with medical technology and clinical expertise. Such integration will have a major impact on health care in the future.
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