Chaofan Jin , Yuan Wang , Lu Wang , Xingjie Zan , Sicheng Tang
{"title":"Oxazine-based molecular switches with finely tunable pH and temperature sensitivity via substituent engineering†","authors":"Chaofan Jin , Yuan Wang , Lu Wang , Xingjie Zan , Sicheng Tang","doi":"10.1039/d5cc00684h","DOIUrl":null,"url":null,"abstract":"<div><div>We report oxazine-coumarin molecular switches with tunable pH and temperature sensitivity achieved through <em>para</em>-substituent engineering. The switches show pH transition points spanning three units with Hammett constant correlation. Strategic pH adjustment reveals a “sweet spot” where temperature sensitivity is synergistically amplified, offering new possibilities for responsive molecular sensors.</div></div>","PeriodicalId":67,"journal":{"name":"Chemical Communications","volume":"61 37","pages":"Pages 6759-6762"},"PeriodicalIF":4.2000,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chemical Communications","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/org/science/article/pii/S1359734525007153","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
We report oxazine-coumarin molecular switches with tunable pH and temperature sensitivity achieved through para-substituent engineering. The switches show pH transition points spanning three units with Hammett constant correlation. Strategic pH adjustment reveals a “sweet spot” where temperature sensitivity is synergistically amplified, offering new possibilities for responsive molecular sensors.
期刊介绍:
ChemComm (Chemical Communications) is renowned as the fastest publisher of articles providing information on new avenues of research, drawn from all the world''s major areas of chemical research.