Oxazine-based molecular switches with finely tunable pH and temperature sensitivity via substituent engineering†

IF 4.2 2区 化学 Q2 CHEMISTRY, MULTIDISCIPLINARY Chemical Communications Pub Date : 2025-04-09 DOI:10.1039/d5cc00684h
Chaofan Jin , Yuan Wang , Lu Wang , Xingjie Zan , Sicheng Tang
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Abstract

We report oxazine-coumarin molecular switches with tunable pH and temperature sensitivity achieved through para-substituent engineering. The switches show pH transition points spanning three units with Hammett constant correlation. Strategic pH adjustment reveals a “sweet spot” where temperature sensitivity is synergistically amplified, offering new possibilities for responsive molecular sensors.

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通过取代基工程实现 pH 值和温度敏感性可微调的恶嗪基分子开关
我们报道了通过对取代基工程实现的具有可调pH和温度敏感性的恶嗪-香豆素分子开关。开关显示pH转变点跨越三个单位,具有Hammett常数相关。战略性的pH值调整揭示了温度敏感性协同放大的“最佳点”,为响应式分子传感器提供了新的可能性。
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来源期刊
Chemical Communications
Chemical Communications 化学-化学综合
CiteScore
8.60
自引率
4.10%
发文量
2705
审稿时长
1.4 months
期刊介绍: ChemComm (Chemical Communications) is renowned as the fastest publisher of articles providing information on new avenues of research, drawn from all the world''s major areas of chemical research.
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