Long COVID update: respiratory sequelae and symptoms.

IF 2 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Current Opinion in Supportive and Palliative Care Pub Date : 2025-06-01 Epub Date: 2025-04-02 DOI:10.1097/SPC.0000000000000755
Muhammad Mamoon Iqbal, Ayesha Iqbal, Rachael A Evans
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Abstract

Purpose of review: Long COVID affects approximately 6% of the population after SARS-CoV-2 infection commonly involving persistent respiratory symptoms such as breathlessness and cough. This review provides an update on the latest evidence regarding post-COVID condition/Long COVID and respiratory sequelae, focusing on persistent symptoms, respiratory complications, and therapeutic approaches to date.

Recent findings: Post-COVID interstitial lung abnormalities are estimated to persist in approximately 11% of patients hospitalized with acute COVID-19. However, breathlessness is common in adults (non-hospitalized) with Long COVID, suggesting aetiologies beyond pneumonitis. The risk of venous thromboembolic disease in Long COVID remains uncertain and trial results of anti-coagulation in Long COVID are awaited.

Summary: Long COVID presents complex respiratory challenges, and careful assessment is crucial to differentiate Long COVID symptoms from exacerbations of pre-existing respiratory conditions. Current management includes a symptom-based multidisciplinary approach, with ongoing research into effective treatments including immune modulating agents.

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COVID 长期更新:呼吸系统后遗症和症状。
综述目的:长冠状病毒影响约6%的SARS-CoV-2感染后的人群,通常涉及持续的呼吸系统症状,如呼吸困难和咳嗽。这篇综述提供了关于COVID后状态/长COVID和呼吸后遗症的最新证据,重点是持续症状、呼吸并发症和迄今为止的治疗方法。最新发现:估计约11%的急性COVID-19住院患者在COVID-19后肺间质性异常持续存在。然而,呼吸困难在患有长冠状病毒的成年人(非住院)中很常见,这表明肺炎以外的病因。长冠状病毒患者发生静脉血栓栓塞性疾病的风险仍不确定,长冠状病毒患者抗凝治疗的试验结果尚待确定。总结:长冠肺炎带来了复杂的呼吸道挑战,仔细评估对于区分长冠肺炎症状与已有呼吸道疾病的恶化至关重要。目前的管理包括基于症状的多学科方法,目前正在研究有效的治疗方法,包括免疫调节剂。
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来源期刊
Current Opinion in Supportive and Palliative Care
Current Opinion in Supportive and Palliative Care HEALTH CARE SCIENCES & SERVICES-
CiteScore
3.70
自引率
0.00%
发文量
54
期刊介绍: A reader-friendly resource, Current Opinion in Supportive and Palliative Care provides an up-to-date account of the most important advances in the field of supportive and palliative care. Each issue contains either two or three sections delivering a diverse and comprehensive coverage of all the key issues, including end-of-life management, gastrointestinal systems and respiratory problems. Current Opinion in Supportive and Palliative Care is an indispensable journal for the busy clinician, researcher or student.
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