[Update on papillary thyroid cancer-What is relevant for surgeons?]

Chirurgie (Heidelberg, Germany) Pub Date : 2025-07-01 Epub Date: 2025-04-02 DOI:10.1007/s00104-025-02275-2
Ann-Kathrin Lederer, Thomas J Musholt
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Abstract

Papillary thyroid cancer (PTC) is the most frequent malignant thyroid tumor in Germany. The diagnosis can only be confirmed by histological examination of the suspicious tissue. The clinical signs, sonographic findings, and the results of fine-needle aspiration, possibly supplemented by subsequent molecular genetic analysis, can confirm the suspected diagnosis before surgery. The prognosis is very good if the diagnosis is made early and, depending on the size of the tumor, complete surgical removal is achieved, with a 10-year survival rate of more than 90%; however, histologically PTC has several variants that are associated with either a high or low risk of metastases and recurrence in patients. Therefore, the extent of necessary treatment, in particular surgical interventions for PTC has been discussed for years. This article provides an overview of the current knowledge on the diagnosis, treatment and prognosis of PTC.

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[甲状腺乳头状癌的最新进展-对外科医生有什么意义?]]
甲状腺乳头状癌(PTC)是德国最常见的恶性甲状腺肿瘤。诊断只能通过可疑组织的组织学检查来证实。临床体征、超声表现和细针穿刺结果,可能辅以随后的分子遗传学分析,可以在手术前证实疑似诊断。如果早期诊断,根据肿瘤的大小,完全手术切除,预后非常好,10年生存率超过90%;然而,组织学上PTC有几种变体,这些变体与患者转移和复发的高风险或低风险相关。因此,PTC的必要治疗程度,特别是手术干预已经讨论多年。本文就PTC的诊断、治疗和预后方面的最新知识作一综述。
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