Sarah C Totton, Jan M Sargeant, Annette M O'Connor
{"title":"Incomplete reporting in randomized controlled trials of bovine respiratory disease vaccines in feedlot cattle.","authors":"Sarah C Totton, Jan M Sargeant, Annette M O'Connor","doi":"10.2460/ajvr.24.12.0389","DOIUrl":null,"url":null,"abstract":"<p><p>We evaluated bovine respiratory disease vaccine trials in feedlot cattle and found that most (19 of 34 [56%]) publications (describing 26 of 43 [60%] trials) labeled the control group as \"unvaccinated\" or similar terms even when all cattle in the trial received vaccine(s) at feedlot arrival. Additionally, 38 of 44 (86%) publications (describing 31 of 53 [58%] trials) reported statistical comparisons of bovine respiratory disease vaccines that did not mention the respiratory vaccines that all cattle received at feedlot arrival. Trial authors should report animal health products given to all cattle in a trial, in the abstract, methods, and results sections, to prevent misinterpretation of the actual comparisons investigated.</p>","PeriodicalId":7754,"journal":{"name":"American journal of veterinary research","volume":" ","pages":""},"PeriodicalIF":1.4000,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"American journal of veterinary research","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.2460/ajvr.24.12.0389","RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/7/1 0:00:00","PubModel":"Print","JCR":"Q2","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
We evaluated bovine respiratory disease vaccine trials in feedlot cattle and found that most (19 of 34 [56%]) publications (describing 26 of 43 [60%] trials) labeled the control group as "unvaccinated" or similar terms even when all cattle in the trial received vaccine(s) at feedlot arrival. Additionally, 38 of 44 (86%) publications (describing 31 of 53 [58%] trials) reported statistical comparisons of bovine respiratory disease vaccines that did not mention the respiratory vaccines that all cattle received at feedlot arrival. Trial authors should report animal health products given to all cattle in a trial, in the abstract, methods, and results sections, to prevent misinterpretation of the actual comparisons investigated.
期刊介绍：
The American Journal of Veterinary Research supports the collaborative exchange of information between researchers and clinicians by publishing novel research findings that bridge the gulf between basic research and clinical practice or that help to translate laboratory research and preclinical studies to the development of clinical trials and clinical practice. The journal welcomes submission of high-quality original studies and review articles in a wide range of scientific fields, including anatomy, anesthesiology, animal welfare, behavior, epidemiology, genetics, heredity, infectious disease, molecular biology, oncology, pharmacology, pathogenic mechanisms, physiology, surgery, theriogenology, toxicology, and vaccinology. Species of interest include production animals, companion animals, equids, exotic animals, birds, reptiles, and wild and marine animals. Reports of laboratory animal studies and studies involving the use of animals as experimental models of human diseases are considered only when the study results are of demonstrable benefit to the species used in the research or to another species of veterinary interest. Other fields of interest or animals species are not necessarily excluded from consideration, but such reports must focus on novel research findings. Submitted papers must make an original and substantial contribution to the veterinary medicine knowledge base; preliminary studies are not appropriate.
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