Emergence of Salmonella enterica carrying bla OXA-181 carbapenemase gene, Italy, 2021 to 2024.

IF 7.8 2区 医学 Q1 INFECTIOUS DISEASES Eurosurveillance Pub Date : 2025-04-01 DOI:10.2807/1560-7917.ES.2025.30.13.2500175
Luca Bolzoni, Erika Scaltriti, Chiara Bracchi, Sara Angelone, Ilaria Menozzi, Roberta Taddei, Patricia Alba, Virginia Carfora, Elena Lavinia Diaconu, Marina Morganti, Alessandra Dodi, Melissa Berni, Laura Manni, Massimiliano Vinci, Martina Tambassi, Laura Mazzera, Irene Venturelli, Simone Ambretti, Antonio Battisti, Stefano Pongolini
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Abstract

Between 2021 and 2024, we detected carbapenemase gene blaOXA-181 in 16 of 11,398 Salmonella enterica (SE) isolates: 10 SE 1,4,[5],12:i:-, three Bovismorbificans, two London and one Rissen from pigs, humans, pork meat and wild roe deer. The gene was first detected in pig isolates, later in humans, suggesting zoonotic transmission. Phylogenetic analysis indicated that horizontal transfer, mainly through plasmids, contributed to the spread. These findings highlight a possible emerging public health threat and the importance of One Health surveillance.

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携带bla OXA-181碳青霉烯酶基因的肠沙门氏菌的出现,意大利,2021 - 2024。
从猪、人、猪肉和野生狍子分离的11398株肠沙门氏菌(SE)中,检测出16株碳青霉烯酶blaOXA-181基因,其中10株为SE 1、4、[5]、12:i:-, 3株为bovismorificans, 2株为London,1株为Rissen。该基因首先在猪分离株中发现,后来在人类中发现,表明人畜共患传播。系统发育分析表明,主要通过质粒的水平转移有助于传播。这些发现突出了可能出现的公共卫生威胁以及“同一个健康”监测的重要性。
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来源期刊
Eurosurveillance
Eurosurveillance INFECTIOUS DISEASES-
CiteScore
32.70
自引率
2.10%
发文量
430
审稿时长
3-8 weeks
期刊介绍: Eurosurveillance is a European peer-reviewed journal focusing on the epidemiology, surveillance, prevention, and control of communicable diseases relevant to Europe.It is a weekly online journal, with 50 issues per year published on Thursdays. The journal includes short rapid communications, in-depth research articles, surveillance reports, reviews, and perspective papers. It excels in timely publication of authoritative papers on ongoing outbreaks or other public health events. Under special circumstances when current events need to be urgently communicated to readers for rapid public health action, e-alerts can be released outside of the regular publishing schedule. Additionally, topical compilations and special issues may be provided in PDF format.
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