{"title":"Glycolaldehyde affects the growth of and metabolic flux distribution in Synechocystis sp. PCC 6803.","authors":"Tatsumi Imada, Yoshihiro Toya, Hiroshi Shimizu","doi":"10.1093/bbb/zbaf046","DOIUrl":null,"url":null,"abstract":"<p><p>Glycolaldehyde (GA) is widely used as a photosynthetic inhibitor to suppress metabolic reactions. We aimed to evaluate the effects of GA on the growth of and metabolic flux distribution in Synechocystis sp. PCC 6803. GA significantly inhibited the growth [half-maximal inhibitory concentration (IC50) = 244 μm] and metabolic flux through the Calvin-Benson-Bassham cycle without decrease in flux of the pentose phosphate pathway.</p>","PeriodicalId":9175,"journal":{"name":"Bioscience, Biotechnology, and Biochemistry","volume":" ","pages":"995-999"},"PeriodicalIF":1.3000,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bioscience, Biotechnology, and Biochemistry","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1093/bbb/zbaf046","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Glycolaldehyde (GA) is widely used as a photosynthetic inhibitor to suppress metabolic reactions. We aimed to evaluate the effects of GA on the growth of and metabolic flux distribution in Synechocystis sp. PCC 6803. GA significantly inhibited the growth [half-maximal inhibitory concentration (IC50) = 244 μm] and metabolic flux through the Calvin-Benson-Bassham cycle without decrease in flux of the pentose phosphate pathway.
期刊介绍：
Bioscience, Biotechnology, and Biochemistry publishes high-quality papers providing chemical and biological analyses of vital phenomena exhibited by animals, plants, and microorganisms, the chemical structures and functions of their products, and related matters. The Journal plays a major role in communicating to a global audience outstanding basic and applied research in all fields subsumed by the Japan Society for Bioscience, Biotechnology, and Agrochemistry (JSBBA).
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