Cancer Diagnosis Optimization With a Combination of Flexible THz Antennas and Machine Learning

IF 2 Q3 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS Engineering reports : open access Pub Date : 2025-04-07 DOI:10.1002/eng2.70120
M. Senthil Pandian, S. Deepa Nivethika, J. Idhikash, Vamsee N. Yashwanth, Aishwarya Shaji, Prabhakaran Paulraj
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Abstract

Cancer continues to be a leading cause of mortality worldwide, emphasizing the importance of early detection for effective treatment. Macroscopic methods like X-ray and CT scans offer limited resolution and pose risks due to ionizing radiation exposure. In contrast, microscopic techniques such as histopathology require invasive biopsy samples and lack real-time diagnostic capabilities. Bridging this gap, THz research offers a promising solution, utilizing nonionizing terahertz radiation to achieve superior resolution. To this end, a proposed microstrip antenna emerges as a cost-effective and high-resolution tool for enabling the accurate diagnosis and detection of superficial cancers. This novel approach could revolutionize medical involvement, leading to earlier cancer detection and improved patient outcomes. The THz antenna of size 526 μm × 536 μm designed using Computer Simulation Technology (CST) software radiates at 0.3 THz with a gain of 5 dB. The antenna, when placed in the model replicating human tissue (Phantom model) radiates at 0.88 THz with a return loss of −27 dB and a gain 10 dB. Whereas, the same antenna was designed and simulated with a model replicating human tissue with tumor, radiating at 0.88 THz with a return loss of −38 dB and gain of 9.6 dB. The optimization of the decision was done using the combination of K-means and logistic regression algorithm to determine 95.06% efficiency.

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柔性太赫兹天线与机器学习相结合的癌症诊断优化
癌症仍然是世界范围内死亡的主要原因,强调了早期发现对有效治疗的重要性。x射线和CT扫描等宏观方法分辨率有限,并且由于电离辐射暴露而存在风险。相比之下,显微技术,如组织病理学,需要侵入性活检样本,缺乏实时诊断能力。太赫兹研究提供了一个很有前途的解决方案,利用非电离太赫兹辐射来实现更高的分辨率。为此,提出的微带天线作为一种成本效益高、高分辨率的工具出现,能够准确诊断和检测浅表癌症。这种新颖的方法可以彻底改变医疗参与,导致早期癌症检测和改善患者的结果。采用CST软件设计的尺寸为526 μm × 536 μm的太赫兹天线辐射频率为0.3太赫兹,增益为5db。当天线放置在复制人体组织的模型(幻影模型)中时,辐射频率为0.88太赫兹,回波损耗为- 27 dB,增益为10 dB。然而,同样的天线设计并模拟了一个复制人体肿瘤组织的模型,辐射频率为0.88太赫兹,回波损耗为−38 dB,增益为9.6 dB。结合K-means和logistic回归算法对决策进行优化,确定效率为95.06%。
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5.10
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审稿时长
19 weeks
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