Retention in Care After Transition to Adult Care for Adolescents and Young Adults With HIV: A Systematic Review and Meta-Analysis.

IF 2.4 3区医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH International Journal of Public Health Pub Date : 2025-03-24 eCollection Date: 2025-01-01 DOI:10.3389/ijph.2025.1607733

Mulugeta Shegaze Shimbre, Abebe Gedefaw Belete, Tamirat Gezahegn Guyo, Wei Ma

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Abstract

Objective: To evaluate the retention rates of adolescents and young adults (aged 10-25 years) living with HIV during the transition to adult HIV care.

Methods: The study involved 15 cohort studies conducted since 2015, focusing on adolescents and young adults aged 10-25 years living with HIV who transitioned to adult care. The primary outcome measured was the retention rate in care after transition. Data screening and extraction were performed using Covidence software, and the quality of included studies was assessed using the Joanna Briggs Institute tool.

Results: The pooled 1-year retention rate was 81% (95% CI: 78%, 91%), while the 2-year retention rate was 69% (95% CI: 53%, 83%). Significant heterogeneity was observed between studies (I² = 96.73%). Subgroup analyses revealed geographical differences, with Asia exhibiting the highest retention rates. Retrospective study designs yielded better retention outcomes.

Conclusion: The findings underscore the challenges and variability in retention rates for adolescents transitioning to adult HIV care. There is a critical need for targeted interventions and improved follow-up strategies to enhance retention and meet global HIV care targets.

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青少年和青年艾滋病毒感染者过渡到成人护理后的护理保留：系统回顾和荟萃分析。

目的：评估感染艾滋病毒的青少年和年轻人（10-25岁）在向成人艾滋病毒护理过渡期间的保留率。方法：该研究纳入了2015年以来开展的15项队列研究，重点关注10-25岁的青少年和年轻人，他们感染了艾滋病毒，并向成人护理过渡。测量的主要结果是转换后护理的保留率。使用covid - ence软件进行数据筛选和提取，使用Joanna Briggs Institute工具评估纳入研究的质量。结果：合并1年保留率为81% (95% CI: 78%, 91%)，合并2年保留率为69% （95% CI: 53%, 83%）。研究间存在显著异质性（I2 = 96.73%）。亚组分析揭示了地域差异，亚洲表现出最高的留存率。回顾性研究设计产生了更好的保留结果。结论：研究结果强调了青少年过渡到成人艾滋病毒护理的保留率的挑战和可变性。迫切需要有针对性的干预措施和改进的后续战略，以提高保留率并实现全球艾滋病毒护理目标。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Journal of Public Health 医学-公共卫生、环境卫生与职业卫生

CiteScore

4.20

自引率

2.20%

发文量

269

审稿时长

12 months

期刊介绍： The International Journal of Public Health publishes scientific articles relevant to global public health, from different countries and cultures, and assembles them into issues that raise awareness and understanding of public health problems and solutions. The Journal welcomes submissions of original research, critical and relevant reviews, methodological papers and manuscripts that emphasize theoretical content. IJPH sometimes publishes commentaries and opinions. Special issues highlight key areas of current research. The Editorial Board''s mission is to provide a thoughtful forum for contemporary issues and challenges in global public health research and practice.