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Access to Essential Medicines in Low- and Middle-Income Countries: A Systematic Review of Barriers and Facilitators. 低收入和中等收入国家获得基本药物:对障碍和促进因素的系统审查。
IF 2.4 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-23 eCollection Date: 2026-01-01 DOI: 10.3389/ijph.2026.1608754
Israel Herrera-Ramirez, Emanuel Orozco-Nuñez, Germán Guerra, Anahi Dreser-Mansilla, Raul Enrique Molina-Salazar

Objectives: To conduct a systematic review to analyze the barriers and facilitators related to accessing essential medicines in low- and middle-income countries (LMICs).

Methods: We searched PubMed, SciELO, LILACS, and Web of Science for studies published between 2002 and 2025. Studies were included if they were peer-reviewed, written in English or Spanish, and reported data on barriers or facilitators across three dimensions: availability, affordability, and adequate use.

Results: From 1010 identified records, 36 studies were included. Most were quantitative (n = 26), followed by qualitative (n = 8) and mixed-methods (n = 2) designs. Barriers (n = 34 studies) were reported more frequently than facilitators (n = 25), particularly for availability and affordability. Key barriers included public sector stock-outs and high prices in the private sector. A key facilitator was the presence of a national essential medicines list.

Conclusion: Our analysis compiles evidence on barriers and facilitators affecting access to essential medicines in LMICs. Policies favoring generic drug procurement and public-private sector disparities highlight the complexity of ensuring equitable access.

目的:进行系统审查,分析中低收入国家在获取基本药物方面存在的障碍和促进因素。方法:检索PubMed、SciELO、LILACS和Web of Science,检索2002年至2025年间发表的研究。如果研究经过同行评审,用英语或西班牙语撰写,并报告了可获得性、可负担性和充分使用这三个方面的障碍或促进因素的数据,则将其纳入研究。结果:从1010份确定的记录中,纳入了36项研究。大多数是定量设计(n = 26),其次是定性设计(n = 8)和混合设计(n = 2)。障碍(n = 34项研究)的报告频率高于促进者(n = 25),特别是在可获得性和可负担性方面。主要障碍包括公共部门缺货和私营部门价格高企。一个关键的促进因素是国家基本药物清单的存在。结论:我们的分析汇编了影响中低收入国家获得基本药物的障碍和促进因素的证据。支持仿制药采购的政策和公私部门差距突出了确保公平获取的复杂性。
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引用次数: 0
Predicting Dementia Risk: Progress, Pitfalls, and Priorities. 预测痴呆风险:进展、缺陷和优先事项。
IF 2.4 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-22 eCollection Date: 2026-01-01 DOI: 10.3389/ijph.2026.1609520
Patricia Nistor, Osvaldo Espin-Garcia, Zul Merali, Shehzad Ali
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引用次数: 0
Corrigendum: Spatial Accessibility Analysis of Snake Antivenom. 勘误:抗蛇毒血清的空间可及性分析。
IF 2.4 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-22 eCollection Date: 2026-01-01 DOI: 10.3389/ijph.2026.1609456
Wenjie Hao, Lanfen He, Xingyue Song, Juntao Wang, Yanlan Hu, Yu Chen, Chuanzhu Lv, Shijiao Yan

[This corrects the article DOI: 10.3389/ijph.2024.1606903.].

[这更正了文章DOI: 10.3389/ijph.2024.1606903.]。
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引用次数: 0
Eligibility for Lung Cancer Screening in Switzerland: A Comparative Analysis of Three Data Sources From Lausanne and the Canton of Vaud. 瑞士肺癌筛查的资格:来自洛桑和沃州的三个数据来源的比较分析
IF 2.4 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-21 eCollection Date: 2026-01-01 DOI: 10.3389/ijph.2026.1609104
Louis Gros, Cynthia Schneider, May-Lucie Meyer, Julie Korber, Yves Henchoz, Julien Vaucher, Pedro Marques-Vidal, Kevin Ten Haaf, Chiara Pozzessere, Cédric Bongard, Christophe Von Garnier, Jean-Luc Bulliard, Kevin Selby

Objectives: This study aimed to estimate the proportion of individuals potentially eligible for lung cancer screening in Lausanne, canton of Vaud, Switzerland, and its associations with key sociodemographic and health-related covariates.

Methods: We analyzed self-reported, cross-sectional data from three sources: Lausanne cohort 65+ (2014; n = 1,678; ages 65-70), CoLaus|PsyCoLaus (2014-2017; n = 3,839; ages 50-79), and the Swiss Health Survey (2022, representative of Vaud, ages 50-79). Eligibility was defined by the 2021 United States Preventive Services Task Force criteria. Screening eligibility prevalence was estimated separately in each dataset, and eligible and non-eligible participants were compared using bivariate hypothesis tests.

Results: Eligibility was 18.2% in the Lc65+ cohort, 16.0% in CoLaus, and 14.4% in the Swiss Health Survey. Among eligible individuals, the prevalence of current smoking was 58.7% in Lc65+, 60.1% in the Swiss Health Survey, and 64.9% in CoLaus. Eligible participants tended to have a higher burden of comorbidities and social vulnerabilities, including cardiovascular disease, metabolic syndrome, depression, and lower education or income; statistically significant differences varied by dataset.

Conclusion: In this Swiss population, about one in six adults met lung cancer screening criteria. Findings highlight the need for combining early detection with tobacco cessation, health promotion, and equitable access to care.

目的:本研究旨在估计瑞士沃州洛桑潜在适合肺癌筛查的个体比例,及其与关键社会人口统计学和健康相关协变量的关联。方法:我们分析了来自三个来源的自我报告的横断面数据:洛桑队列65+(2014年;n = 1678;年龄65-70)、CoLaus|PsyCoLaus(2014-2017年;n = 3839;年龄50-79)和瑞士健康调查(2022年,代表沃州,年龄50-79)。资格由2021年美国预防服务工作组标准定义。在每个数据集中分别估计筛查合格率,并使用双变量假设检验比较合格和不合格的参与者。结果:Lc65+组的适格率为18.2%,CoLaus组为16.0%,瑞士健康调查组为14.4%。在符合条件的个体中,Lc65+的当前吸烟率为58.7%,瑞士健康调查为60.1%,科罗拉多州为64.9%。符合条件的参与者往往有较高的合并症负担和社会脆弱性,包括心血管疾病、代谢综合征、抑郁症和较低的教育或收入;统计上的显著差异因数据集而异。结论:在瑞士人群中,大约六分之一的成年人符合肺癌筛查标准。调查结果强调需要将早期发现与戒烟、促进健康和公平获得保健结合起来。
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引用次数: 0
Pushing the Boundaries of Health Self-Management With Conversational AI. 用对话式人工智能推动健康自我管理的界限。
IF 2.4 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-16 eCollection Date: 2026-01-01 DOI: 10.3389/ijph.2026.1608975
Enxhi Qama
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引用次数: 0
Effective Communication Within and Across Public Health Institutions: A Qualitative Study in Switzerland. 公共卫生机构内部和机构之间的有效沟通:瑞士的一项定性研究。
IF 2.4 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-08 eCollection Date: 2025-01-01 DOI: 10.3389/ijph.2025.1609055
Maddalena Fiordelli, Nicola Diviani, Alexander Ort, Sara Rubinelli

Objectives: This paper explores the communication challenges faced by public health institutions in Switzerland during COVID-19 pandemic and identifies key barriers and facilitators of effective communication within and across public health institutions.

Methods: In 2021, we conducted qualitative online semi-structured interviews to collect opinions and experiences of representatives of Swiss public health institutions. Interview transcripts were analyzed using inductive thematic analysis to identify main themes.

Results: Key facilitators of effective communication included flexibility, dedicated resources, new processes, coordination, and experiential knowledge. Inter-institutional communication benefited from clear processes, active listening, mediation, and strong networks. Barriers mirrored these factors, such as role tensions, unclear responsibilities, and limited resources. Discrepancies across cantons and between government levels, especially between the confederation and cantons, often hindered communication.

Conclusion: To strengthen communication in public health crises, we recommend clear protocols, centralized structures, and bridging cultural and linguistic gaps. Ongoing training and diverse perspectives are key to effective communication within and across public health institutions in Switzerland and beyond.

目的:本文探讨了瑞士公共卫生机构在COVID-19大流行期间面临的沟通挑战,并确定了公共卫生机构内部和之间有效沟通的主要障碍和促进因素。方法:在2021年,我们进行了定性的在线半结构化访谈,收集瑞士公共卫生机构代表的意见和经验。访谈记录分析使用归纳主题分析,以确定主要主题。结果:有效沟通的关键促进因素包括灵活性、专用资源、新流程、协调和经验知识。机构间沟通得益于明确的流程、积极的倾听、调解和强大的网络。障碍反映了这些因素,如角色紧张、责任不明确和资源有限。各州之间和各级政府之间的差异,特别是联邦和各州之间的差异,经常阻碍沟通。结论:为了加强公共卫生危机中的沟通,我们建议制定明确的协议,集中结构,弥合文化和语言差距。持续的培训和多样化的观点是瑞士内外公共卫生机构之间有效沟通的关键。
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引用次数: 0
Mapping the Dynamic Complexity of Hypertension Management in São Paulo, Brazil. 绘制巴西圣保罗高血压管理的动态复杂性。
IF 2.4 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-07 eCollection Date: 2025-01-01 DOI: 10.3389/ijph.2025.1608895
Pei Shan Loo, Anna Socha, Mariana Silveira, Yara Carnevalli Baxter, Álvaro Avezum, Luciano F Drager, Luiz A Bortolotto, Johannes Boch, Daniel Cobos Munoz

Objectives: Hypertension is a major cardiovascular risk factor in Brazil and globally, requiring effective healthcare system strategies. This study examines how the health system in São Paulo manages hypertension, identifying patterns and connections that influence patient outcomes and resource use.

Methods: Using literature reviews and participatory discussions with experts, we developed a systems map, causal loop diagram, to illustrate dynamic complexity underpinning hypertension management. Thematic analysis of qualitative data informed the model, highlighting key interactions that shape screening, treatment, and long-term care.

Results: The analysis reveals critical dynamics at individual, community, and system levels. Early diagnosis and expanded treatment access improve adherence and reduce complications. However, these improvements also increase the number of patients needing long-term care. This creates a challenge where healthcare gains today can raise future demands if prevention efforts are underfunded.

Conclusion: Understanding these interconnections is crucial for balancing treatment expansion with sustainable prevention strategies. By mapping system-wide challenges, this study offers a framework to help policymakers allocate resources more effectively and strengthen urban health systems. Future research will focus on using simulation modeling to test policy interventions and improve hypertension outcomes.

目的:高血压是巴西和全球主要的心血管危险因素,需要有效的医疗保健系统策略。本研究考察了圣保罗卫生系统如何管理高血压,确定影响患者预后和资源使用的模式和联系。方法:通过文献回顾和与专家的参与式讨论,我们开发了一个系统图,因果循环图,来说明支撑高血压管理的动态复杂性。定性数据的专题分析为模型提供了信息,强调了影响筛查、治疗和长期护理的关键相互作用。结果:分析揭示了个人、社区和系统层面的关键动态。早期诊断和扩大治疗可改善依从性并减少并发症。然而,这些改善也增加了需要长期护理的患者数量。这造成了一个挑战,即如果预防工作资金不足,今天的卫生保健成果可能会提高未来的需求。结论:了解这些相互关系对于平衡治疗扩展与可持续预防策略至关重要。通过绘制全系统挑战地图,本研究提供了一个框架,帮助决策者更有效地分配资源并加强城市卫生系统。未来的研究将集中在使用模拟建模来测试政策干预和改善高血压预后。
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引用次数: 0
Editorial: The Impact of Ultra-Processed Food Consumption on Health in Low- and Middle-Income Countries. 社论:中低收入国家超加工食品消费对健康的影响。
IF 2.4 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-05 eCollection Date: 2025-01-01 DOI: 10.3389/ijph.2025.1609418
Marialaura Bonaccio, Sukshma Sharma, Licia Iacoviello
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引用次数: 0
Why Scientists Must Engage: Environmental Health in Times of Armed Conflict. 为什么科学家必须参与:武装冲突时期的环境健康。
IF 2.4 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-12-17 eCollection Date: 2025-01-01 DOI: 10.3389/ijph.2025.1609353
Manolis Kogevinas, Marianthi-Anna Kioumourtzoglou, Amira Aker, Anass Houdou, Stephanie Grady, Aziza Menouni, Youssef Oulhote, Beate Ritz, Ellen M Wells, Wael K Al-Delaimy
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引用次数: 0
Burden and Challenges of Managing Hypertension in People Living with Human Immunodeficiency Virus (HIV) Infection in Sub-Saharan Africa: A Mixed Systematic Review and Meta-Analysis. 撒哈拉以南非洲人类免疫缺陷病毒(HIV)感染者高血压管理的负担和挑战:一项混合系统评价和荟萃分析
IF 2.4 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-12-17 eCollection Date: 2025-01-01 DOI: 10.3389/ijph.2025.1608521
Francis Duhamel Nang Nang, Liliane Mfeukeu Kuate, Anastase Dzudie, Fabrice Djouma Nimbot, Paul Junior Chebo, Luc Baudoin Fankoua Tchaptcha, André Pascal Kengne, Jean Pierre Junior Tchitetchoun, François Anicet Onana Akoa, Rita Marie Ifoue, Lawson Ngwagwe Mbolueh, Charles Kouanfack, Simeon Pierre Choukem

Objectives: Poor hypertension prevention among people living with HIV (PLHIV) in sub-Saharan Africa may undermine progress in HIV prevention achieved within this population. This review synthesizes data on the prevalence, diagnosis, treatment, control, and challenges related to hypertension prevention among PLHIV in SSA.

Methods: A mixed-method systematic review with meta-analysis was conducted from January to December 2024. Data analysis was performed using random-effects modeling stratified by age and sex, along with thematic analysis. The JBI critical appraisal tool was used to assess study quality.

Results: A total of 31 studies, including 32286 PLHIV (±37 years old), were included. Hypertension affected 25% [95% CI, 21%-28%] of PLHIV, yet only 34% [95% CI, 11%-64%] of cases received treatment, and 19% [95% CI, 3%-34%] had controlled blood pressure, despite BP measurement in 95% [95% CI, 89%-100%] of them.

Conclusion: Hypertension prevention challenges stem from patient-related factors, healthcare providers, and health system gaps. Despite the high prevalence of hypertension among PLHIV, treatment initiation and blood pressure control rates remain low. Strengthening the integration of HIV and hypertension care services is urgently needed.

目的:撒哈拉以南非洲地区艾滋病毒感染者(PLHIV)高血压预防不力可能会破坏该人群在预防艾滋病毒方面取得的进展。本综述综合了SSA地区PLHIV患病率、诊断、治疗、控制和高血压预防相关挑战的数据。方法:于2024年1 - 12月采用混合方法进行系统评价和meta分析。数据分析采用随机效应模型,按年龄和性别分层,并进行专题分析。使用JBI关键评价工具评估研究质量。结果:共纳入31项研究,包括32286例PLHIV(±37岁)。25% [95% CI, 21%-28%]的PLHIV患者患有高血压,但只有34% [95% CI, 11%-64%]的患者接受了治疗,19% [95% CI, 3%-34%]的患者血压得到控制,尽管其中95% [95% CI, 89%-100%]的患者测量了血压。结论:高血压预防挑战源于患者相关因素、卫生保健提供者和卫生系统差距。尽管艾滋病毒感染者中高血压患病率很高,但开始治疗和血压控制率仍然很低。迫切需要加强艾滋病毒和高血压护理服务的整合。
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引用次数: 0
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International Journal of Public Health
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