Precision-Engineered DNA Nanopatches for Enhancing Mesenchymal Stem Cell Therapy in Osteoporosis

IF 9.2 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY CCS Chemistry Pub Date : 2025-04-07 DOI:10.31635/ccschem.025.202405310
Sheng Pan, Xiangbowen Jin, Yufan Ling, Haoliang Shi, Binbin Chu, Xieyidai Ruze, Yike Wang, Yao He, Houyu Wang & Youjia Xu1Department of Orthopaedics, Second Affiliated Hospital of Soochow University, Osteoporosis Research Institute of Soochow University, Suzhou 2150002Suzhou Key Laboratory of Nanotechnology and Biomedicine, Institute of Functional Nano & Soft Materials & Collaborative Innovation Center of Suzhou Nano Science and Technology (NANO-CIC), Soochow University, Suzhou 2151233State Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Suzhou Medical College of Soochow University, Suzhou 215123
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Abstract

CCS Chemistry, Ahead of Print.
Conventional treatments of osteoporosis focus on either inhibiting bone resorption or enhancing osteogenesis but fail to address the osteoporotic microenvironment, particularly the impact of reactive oxygen species (ROS) on bone metabolism. Mesenchymal ...
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精密工程DNA纳米贴片增强骨质疏松症间充质干细胞治疗
CCS化学,领先于印刷。骨质疏松症的传统治疗侧重于抑制骨吸收或促进骨生成,但未能解决骨质疏松微环境,特别是活性氧(ROS)对骨代谢的影响。间充质……
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来源期刊
CCS Chemistry
CCS Chemistry Chemistry-General Chemistry
CiteScore
13.60
自引率
13.40%
发文量
475
审稿时长
10 weeks
期刊介绍: CCS Chemistry, the flagship publication of the Chinese Chemical Society, stands as a leading international chemistry journal based in China. With a commitment to global outreach in both contributions and readership, the journal operates on a fully Open Access model, eliminating subscription fees for contributing authors. Issued monthly, all articles are published online promptly upon reaching final publishable form. Additionally, authors have the option to expedite the posting process through Immediate Online Accepted Article posting, making a PDF of their accepted article available online upon journal acceptance.
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