Li-Ping Feng , Zhan-Guo Li , Qian Ding , Chun Luo , Xue-Ping Lu , Xiao-Hui Li
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引用次数: 0
Abstract
Phytochemical exploration of the fibrous roots of Ophiopogon japonicus culminated in the identification of two novel homoisoflavonoids, designated as 5-O-methylophiopogonone C (1) and (3S)-7,2’-dihydroxy - 3’,4’-methylenedioxyhomoisoflavan (2). Leveraging an array of advanced spectroscopic methodologies, inclusive of nuclear magnetic resonance (NMR), infrared spectroscopy (IR), ultraviolet spectroscopy (UV), and high - resolution electrospray ionization mass spectrometry (HRESIMS), the structures of two isolated compounds were meticulously elucidated. Subsequently, their tyrosine kinase inhibitory activities were evaluated.
期刊介绍：
Phytochemistry Letters invites rapid communications on all aspects of natural product research including:
• Structural elucidation of natural products
• Analytical evaluation of herbal medicines
• Clinical efficacy, safety and pharmacovigilance of herbal medicines
• Natural product biosynthesis
• Natural product synthesis and chemical modification
• Natural product metabolism
• Chemical ecology
• Biotechnology
• Bioassay-guided isolation
• Pharmacognosy
• Pharmacology of natural products
• Metabolomics
• Ethnobotany and traditional usage
• Genetics of natural products
Manuscripts that detail the isolation of just one new compound are not substantial enough to be sent out of review and are out of scope. Furthermore, where pharmacology has been performed on one new compound to increase the amount of novel data, the pharmacology must be substantial and/or related to the medicinal use of the producing organism.
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