Le Mai Hong Tham, Imam Sahroni, Ghina Kifayah Putri, Taiga Kodama, Muhammad Fadil, Takeru Nakahara, Ami Takase, Muhammad Sohail Ahmad, Armando T. Quitain, Yusuke Inomata, Prasert Reubroycharoen and Tetsuya Kida
{"title":"Deuteration of organic compounds by electrolysis of glucose-heavy water using a graphene oxide membrane reactor†","authors":"Le Mai Hong Tham, Imam Sahroni, Ghina Kifayah Putri, Taiga Kodama, Muhammad Fadil, Takeru Nakahara, Ami Takase, Muhammad Sohail Ahmad, Armando T. Quitain, Yusuke Inomata, Prasert Reubroycharoen and Tetsuya Kida","doi":"10.1039/D5CC01646K","DOIUrl":null,"url":null,"abstract":"<p >This study explores the cost-effective synthesis of deuterium-labelled compounds <em>via</em> electrolysis of glucose-heavy water (D<small><sub>2</sub></small>O) employing a proton-conducting graphene oxide membrane (GOM) with Pt/C and IrO<small><sub>2</sub></small>/Al<small><sub>2</sub></small>O<small><sub>3</sub></small>. C(sp<small><sup>3</sup></small>)–H bonds of mono, double, and triple methyl groups in aromatic compounds were successfully deuterated with high deuterium incorporation (%) and excellent yield (%).</p>","PeriodicalId":67,"journal":{"name":"Chemical Communications","volume":" 38","pages":" 6953-6956"},"PeriodicalIF":4.2000,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chemical Communications","FirstCategoryId":"92","ListUrlMain":"https://pubs.rsc.org/en/content/articlelanding/2025/cc/d5cc01646k","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
This study explores the cost-effective synthesis of deuterium-labelled compounds via electrolysis of glucose-heavy water (D2O) employing a proton-conducting graphene oxide membrane (GOM) with Pt/C and IrO2/Al2O3. C(sp3)–H bonds of mono, double, and triple methyl groups in aromatic compounds were successfully deuterated with high deuterium incorporation (%) and excellent yield (%).
期刊介绍：
ChemComm (Chemical Communications) is renowned as the fastest publisher of articles providing information on new avenues of research, drawn from all the world''s major areas of chemical research.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
