A novel fluorescent probe with large stokes shift based on naphthalimide and phenanthroline for specific detection of Ag+ and its application in living cells imaging
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Abstract
Silver ions (Ag+) are widely used in industry and daily life. To achieve the specific and sensitive detection of Ag+, a novel fluorescent probe NP based on naphthalimide-phenanthroline was developed in this study. NP has an emission wavelength of 580 nm and exhibits a large Stokes shift (190 nm), showing a quenching fluorescence response to Ag+. NP can sensitively detect Ag+ with a detection limit as low as 24.6 nM. The response time is only 110 s. In particular, NP demonstrates effective detection of Ag+ in real water samples. In addition, NP exhibits low toxicity and has been successfully applied for Ag+ imaging in Hela cells.
期刊介绍：
Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy (SAA) is an interdisciplinary journal which spans from basic to applied aspects of optical spectroscopy in chemistry, medicine, biology, and materials science.
The journal publishes original scientific papers that feature high-quality spectroscopic data and analysis. From the broad range of optical spectroscopies, the emphasis is on electronic, vibrational or rotational spectra of molecules, rather than on spectroscopy based on magnetic moments.
Criteria for publication in SAA are novelty, uniqueness, and outstanding quality. Routine applications of spectroscopic techniques and computational methods are not appropriate.
Topics of particular interest of Spectrochimica Acta Part A include, but are not limited to:
Spectroscopy and dynamics of bioanalytical, biomedical, environmental, and atmospheric sciences,
Novel experimental techniques or instrumentation for molecular spectroscopy,
Novel theoretical and computational methods,
Novel applications in photochemistry and photobiology,
Novel interpretational approaches as well as advances in data analysis based on electronic or vibrational spectroscopy.
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