Role of bronchoscopic mucus plug removal in the diagnosis and treatment of allergic bronchopulmonary mycosis using the new criteria: A single-centre, retrospective study

IF 2 Q2 RESPIRATORY SYSTEM Respiratory investigation Pub Date : 2025-07-01 Epub Date: 2025-04-17 DOI:10.1016/j.resinv.2025.04.003

Yuki Takigawa, Ken Sato, Shoichiro Matsumoto, Takeru Ichikawa, Tomoyoshi Inoue, Suzuka Matsuoka, Hiromi Watanabe, Kenichiro Kudo, Akiko Sato, Keiichi Fujiwara

{"title":"Role of bronchoscopic mucus plug removal in the diagnosis and treatment of allergic bronchopulmonary mycosis using the new criteria: A single-centre, retrospective study","authors":"Yuki Takigawa, Ken Sato, Shoichiro Matsumoto, Takeru Ichikawa, Tomoyoshi Inoue, Suzuka Matsuoka, Hiromi Watanabe, Kenichiro Kudo, Akiko Sato, Keiichi Fujiwara","doi":"10.1016/j.resinv.2025.04.003","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>The allergic bronchopulmonary mycosis (ABPM) diagnostic criteria that were proposed in 2019 have proven useful in clinical practice due to their high sensitivity and specificity for ABPM diagnosis. By these new criteria, bronchoscopy may be required for diagnosis and treatment of ABPM. Here, we retrospectively reviewed our experience at the NHO Okayama Medical Center to determine the effectiveness of bronchoscopic examination in the management of patients with ABPM.</div></div><div><h3>Method</h3><div>We analyzed the background, laboratory data, computed tomography images, and bronchoscopy results of patients diagnosed with ABPM who were treated at Okayama Medical Center between October 2020 and March 2024.</div></div><div><h3>Result</h3><div>Five of the 10 patients met the new diagnostic criteria for ABPM before bronchoscopic examination. However, after bronchoscopy findings were analyzed, all patients (10/10) met the new inclusion criteria. Fungi cultured from the mucus plugs obtained in four cases as well as cytology revealed the presence of fungus in the mucus plug in six cases. Three patients showed clinical improvement after bronchoscopic removal of the mucus plug.</div></div><div><h3>Conclusion</h3><div>Bronchoscopy performed as part of the new ABPM diagnostic criteria were shown to be efficacious for the diagnosis and treatment of ABPM in our institution.</div></div>","PeriodicalId":20934,"journal":{"name":"Respiratory investigation","volume":"63 4","pages":"Pages 495-499"},"PeriodicalIF":2.0000,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Respiratory investigation","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2212534525000449","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/4/17 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"RESPIRATORY SYSTEM","Score":null,"Total":0}

引用次数: 0

Abstract

Background

The allergic bronchopulmonary mycosis (ABPM) diagnostic criteria that were proposed in 2019 have proven useful in clinical practice due to their high sensitivity and specificity for ABPM diagnosis. By these new criteria, bronchoscopy may be required for diagnosis and treatment of ABPM. Here, we retrospectively reviewed our experience at the NHO Okayama Medical Center to determine the effectiveness of bronchoscopic examination in the management of patients with ABPM.

Method

We analyzed the background, laboratory data, computed tomography images, and bronchoscopy results of patients diagnosed with ABPM who were treated at Okayama Medical Center between October 2020 and March 2024.

Result

Five of the 10 patients met the new diagnostic criteria for ABPM before bronchoscopic examination. However, after bronchoscopy findings were analyzed, all patients (10/10) met the new inclusion criteria. Fungi cultured from the mucus plugs obtained in four cases as well as cytology revealed the presence of fungus in the mucus plug in six cases. Three patients showed clinical improvement after bronchoscopic removal of the mucus plug.

Conclusion

Bronchoscopy performed as part of the new ABPM diagnostic criteria were shown to be efficacious for the diagnosis and treatment of ABPM in our institution.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

支气管镜下粘液塞去除在诊断和治疗过敏性支气管肺真菌病中的作用：一项单中心回顾性研究

2019年提出的过敏性支气管肺真菌病（ABPM）诊断标准因其对ABPM诊断的高敏感性和特异性而在临床实践中被证明是有用的。根据这些新标准，诊断和治疗ABPM可能需要支气管镜检查。在这里，我们回顾性地回顾了我们在NHO冈山医疗中心的经验，以确定支气管镜检查在治疗ABPM患者中的有效性。方法分析2020年10月至2024年3月在冈山医疗中心接受治疗的诊断为ABPM的患者的背景、实验室数据、计算机断层扫描图像和支气管镜检查结果。结果10例患者中有5例在支气管镜检查前符合新的ABPM诊断标准。然而，在分析支气管镜检查结果后，所有患者（10/10）符合新的纳入标准。4例粘液塞真菌培养及细胞学检查显示6例粘液塞真菌存在。3例患者经支气管镜下清除黏液塞后临床改善。结论支气管镜检查作为ABPM新诊断标准的一部分，对本院ABPM的诊断和治疗是有效的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊