Open Repair for Nonruptured Abdominal Aortic Aneurysm in Octogenarians With Prior Abdominal Surgery

IF 1.7 3区 医学 Q2 SURGERY Journal of Surgical Research Pub Date : 2025-05-01 Epub Date: 2025-04-19 DOI:10.1016/j.jss.2025.03.045
Renxi Li BS , Anton Sidawy MD, MPH, FACS , Bao-Ngoc Nguyen MD, FACS
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Abstract

Introduction

Previous abdominal surgery (PAS) has been shown to potentially affect outcomes of open surgical repair (OSR) for abdominal aortic aneurysm (AAA). Octogenarians have been observed to face significantly higher risks following OSR for AAA, which highlights the need for a more cautious selection of their surgical candidacy. This study aimed to assess the association between PAS and the 30-d outcomes of OSR for nonemergent intact AAA among octogenarians.

Methods

Octogenarians (aged ≥80 y) who underwent OSR for AAA were identified in American College of Surgeons National Surgical Quality Improvement Program targeted databases from 2012 to 2022. Exclusion criteria included emergency and ruptured aneurysm. Multivariable logistic regression was used to compare 30-d perioperative outcomes between octogenarians with and without PAS while adjusting for demographics, comorbidities, indications, aneurysm extents, and surgical approaches.

Results

Among 4242 patients who underwent OSR for nonemergent intact AAAs, 562 patients (13.25%) were octogenarians. Among the octogenarians, 173 (30.78%) had PAS, whereas 389 (69.22%) had no history of PAS. Octogenarians with and without PAS had comparable 30-d mortality (10.4% versus 9.51%, adjusted odds ratio 1.104, 95% confidence interval 0.581-2.095, P = 0.76). However, octogenarian patients with PAS had a higher risk of lower extremity ischemia (9.83% versus 4.37%, adjusted odds ratio 2.247, 95% confidence interval 1.064-4.745, P = 0.03). All other 30-d surgical outcomes did not differ between octogenarians with and without PAS. In addition, unplanned reoperation, discharge not to home, 30-d readmission, operation time, and length of stay were not different between the groups.

Conclusions

Octogenarians with a history of PAS had largely similar 30-d mortality and morbidities, except a 2.25 times higher risk of lower extremity ischemia. Therefore, although a history of PAS should not preclude octogenarian patients from undergoing OSR for AAA, additional vigilance for postoperative lower extremity ischemia is warranted to ensure timely and appropriate secondary interventions.
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有腹部手术史的八旬老人未破裂腹主动脉瘤的开放式修复
既往腹部手术(PAS)已被证明可能影响腹主动脉瘤(AAA)开放式手术修复(OSR)的结果。观察到,八十多岁的老年人在AAA的OSR后面临着明显更高的风险,这突出了他们需要更谨慎地选择手术候选人。本研究旨在评估PAS与80多岁非急诊完整AAA患者30 d OSR结果之间的关系。方法在2012 - 2022年美国外科医师学会国家手术质量改进计划的目标数据库中确定了因AAA接受OSR的90多岁(≥80岁)患者。排除标准包括急诊和破裂动脉瘤。采用多变量logistic回归比较80多岁患者有和没有PAS的30天围手术期结果,同时调整人口统计学、合并症、适应症、动脉瘤范围和手术入路。结果4242例非急诊完整AAAs行OSR的患者中,562例(13.25%)为80多岁。80岁以上老人中,有PAS的173人(30.78%),无PAS病史的389人(69.22%)。有和没有PAS的80多岁老人30天死亡率相当(10.4% vs 9.51%,校正优势比1.104,95%可信区间0.581-2.095,P = 0.76)。然而,80岁高龄PAS患者下肢缺血的风险较高(9.83%对4.37%,校正优势比2.247,95%可信区间1.064-4.745,P = 0.03)。所有其他30天的手术结果在有和没有PAS的80多岁老人之间没有差异。非计划再手术、出院不回家、30 d再入院、手术时间、住院时间组间无差异。结论有PAS病史的老年患者30天死亡率和发病率基本相似,但下肢缺血风险高2.25倍。因此,尽管有PAS病史不应排除80多岁的AAA患者接受OSR,但对术后下肢缺血的额外警惕是必要的,以确保及时和适当的二次干预。
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来源期刊
CiteScore
3.90
自引率
4.50%
发文量
627
审稿时长
138 days
期刊介绍: The Journal of Surgical Research: Clinical and Laboratory Investigation publishes original articles concerned with clinical and laboratory investigations relevant to surgical practice and teaching. The journal emphasizes reports of clinical investigations or fundamental research bearing directly on surgical management that will be of general interest to a broad range of surgeons and surgical researchers. The articles presented need not have been the products of surgeons or of surgical laboratories. The Journal of Surgical Research also features review articles and special articles relating to educational, research, or social issues of interest to the academic surgical community.
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