{"title":"Leading developments in basic research on aspergillosis and mucormycosis","authors":"Argha Sarkar , Drauzio E.N. Rangel , Nir Osherov","doi":"10.1016/j.funbio.2025.101574","DOIUrl":null,"url":null,"abstract":"<div><div>This editorial presents an overview of notable contributions in basic research on aspergillosis and mucormycosis published between 2022 and 2024. Basic research in aspergillosis saw major advances in the field of genomics brought about by inexpensive whole-genome sequencing of hundreds of isolates. This has deepened our understanding of <em>Aspergillus fumigatus</em> population structure, gene diversity, and the evolution of azole antifungal resistance. Basic research in mucormycosis saw interesting developments in our understanding of the interactions between <em>Rhizopus microsporus</em> and endosymbiotic bacteria that protect it against predatory soil amoeba and increase its virulence in models of infection.</div></div>","PeriodicalId":12683,"journal":{"name":"Fungal biology","volume":"129 4","pages":"Article 101574"},"PeriodicalIF":3.0000,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Fungal biology","FirstCategoryId":"99","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1878614625000406","RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/4/8 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"MYCOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
This editorial presents an overview of notable contributions in basic research on aspergillosis and mucormycosis published between 2022 and 2024. Basic research in aspergillosis saw major advances in the field of genomics brought about by inexpensive whole-genome sequencing of hundreds of isolates. This has deepened our understanding of Aspergillus fumigatus population structure, gene diversity, and the evolution of azole antifungal resistance. Basic research in mucormycosis saw interesting developments in our understanding of the interactions between Rhizopus microsporus and endosymbiotic bacteria that protect it against predatory soil amoeba and increase its virulence in models of infection.
期刊介绍：
Fungal Biology publishes original contributions in all fields of basic and applied research involving fungi and fungus-like organisms (including oomycetes and slime moulds). Areas of investigation include biodeterioration, biotechnology, cell and developmental biology, ecology, evolution, genetics, geomycology, medical mycology, mutualistic interactions (including lichens and mycorrhizas), physiology, plant pathology, secondary metabolites, and taxonomy and systematics. Submissions on experimental methods are also welcomed. Priority is given to contributions likely to be of interest to a wide international audience.
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