Runhui Yang , Yanli Zhang , Qun Gao , Chenhui Sang , Yumin Niu , Shiyu Du , Bing Shao
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引用次数: 0
Abstract
Fluorinated liquid-crystal monomers (FLCMs) are widespread environmental contaminants with potential endocrine-disrupting effects. Infants are particularly vulnerable, yet their exposure remains unclear. This study analyzed FLCMs in urine samples from 190 paired mothers and infants in Beijing, detecting 34 and 35 FLCMs, respectively. Median creatinine-corrected concentrations were 1.83 μg/g (unadjusted concentrations: 1.28 ng/mL) for mothers and 3.28 μg/g (0.60 ng/mL) for infants. 1-butoxy-2,3-difluoro-4-(trans-4-propylcyclohexyl) benzene (BDPrB) and 1-ethyl-4-[(4-fluorophenyl) ethynyl] benzene (EFPEB) were identified as the primary detected contaminants. A significant positive correlation in urine concentrations between mothers and infants was observed only for 2′-Fluoro-4″-propyl-[1,1':4′,1″-terphenyl]-4-carbonitrile (FPTC) (rs = 0.23, p = 0.023). Certain FLCMs were associated with infant feeding patterns, maternal parity, and environmental exposure, including dust and cleaning frequency (p < 0.05). The results of the study showed that the median estimated daily intakes (EDIs) of ∑FLCMs for mothers and infants were 526 and 425 ng/kg bw/day, respectively, with no significant difference between them (p > 0.05). Further stratification of the data by sex revealed that for male infants, the EDI values for BDPrB and EFPEB were greater (p < 0.05). These findings emphasize the need for greater research on the health effects of FLCMs on infants, particularly considering gender differences.
期刊介绍：
Environmental Pollution is an international peer-reviewed journal that publishes high-quality research papers and review articles covering all aspects of environmental pollution and its impacts on ecosystems and human health.
Subject areas include, but are not limited to:
• Sources and occurrences of pollutants that are clearly defined and measured in environmental compartments, food and food-related items, and human bodies;
• Interlinks between contaminant exposure and biological, ecological, and human health effects, including those of climate change;
• Contaminants of emerging concerns (including but not limited to antibiotic resistant microorganisms or genes, microplastics/nanoplastics, electronic wastes, light, and noise) and/or their biological, ecological, or human health effects;
• Laboratory and field studies on the remediation/mitigation of environmental pollution via new techniques and with clear links to biological, ecological, or human health effects;
• Modeling of pollution processes, patterns, or trends that is of clear environmental and/or human health interest;
• New techniques that measure and examine environmental occurrences, transport, behavior, and effects of pollutants within the environment or the laboratory, provided that they can be clearly used to address problems within regional or global environmental compartments.
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