Lactic acid separation technologies: Enhancing efficiency and purity using membrane separation technology (mini review)

IF 4.2 Q2 CHEMISTRY, MULTIDISCIPLINARY Results in Chemistry Pub Date : 2025-04-18 DOI:10.1016/j.rechem.2025.102280
Nahla. M. Salatein , A.M. Abdelghany , B.M. Elmowafy , Rawan K. Hassan , Ahmed F. Omara , Aziz R. Mansour , Irene S. Fahim
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Abstract

The extraction and purification of lactic acid from fermentation processes is crucial for biotechnological product quality and productivity improvement. This mini review focuses on the topic of lactic acid purification processes that incorporate membrane separation technologies. Membrane filtration isolates lactic acid from fermentation broth without energy-intensive distillation. Membrane techniques involve microfiltration, ultrafiltration, and nanofiltration. The advantages of membrane technology are examined, including lower operational expenses, reduced thermal degradation of lactic acid, and the potential for continuous operation. This paper summarizes our research on the use of membrane separation systems, particularly microfiltration and nanofiltration, for the separation and concentration of lactic acids from fermentation broths derived from sugarcane molasses. Based on the data collected during our study, we have decided to implement membrane technology as the primary method for separation in our future work to enhance the overall efficiency and sustainability of LA production. This integration is expected to improve both the yield and purity of LA, making the production process more economically viable. Consequently, the adoption of these advanced filtration techniques could lead to a more sustainable approach in the bioprocessing industry.

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乳酸分离技术:利用膜分离技术提高效率和纯度(综述)
发酵过程中乳酸的提取和纯化对生物技术产品的质量和生产率的提高至关重要。这篇综述集中在乳酸净化过程的主题,包括膜分离技术。膜过滤从发酵液中分离乳酸,不需要耗能蒸馏。膜技术包括微滤、超滤和纳滤。研究了膜技术的优点,包括较低的操作费用,减少乳酸的热降解,以及连续操作的潜力。本文综述了利用膜分离系统,特别是微滤和纳滤分离和浓缩甘蔗糖蜜发酵液中乳酸的研究进展。根据我们在研究中收集的数据,我们决定在我们未来的工作中采用膜技术作为主要的分离方法,以提高LA生产的整体效率和可持续性。这种整合有望提高LA的收率和纯度,使生产过程更具经济可行性。因此,采用这些先进的过滤技术可以为生物加工工业带来更可持续的方法。
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来源期刊
Results in Chemistry
Results in Chemistry Chemistry-Chemistry (all)
CiteScore
2.70
自引率
8.70%
发文量
380
审稿时长
56 days
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