Wenhao Ouyang , Chenjie Zhu , Yudi Li , Hong Huang , Fangming Li , Li Ling
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引用次数: 0
Abstract
Synthetic chemicals like triethyl citrate (TEC) are widely used in food packaging, pharmaceuticals, and cosmetics. Despite being considered safe, there are concerns about TEC's potential neurotoxic effects. In this study, we used network toxicology and molecular docking to examine TEC's impact on the nervous system. We identified 229 targets related to neurotoxicity and found that TEC may affect key processes such as cell death, inflammation, and neuronal health. Molecular docking showed strong interactions between TEC and proteins like MAPK3, SRC, CASP3, TNF, and BCL2, suggesting a risk of neural damage and the need for further research to assess TEC's safety.
期刊介绍：
Ecotoxicology and Environmental Safety is a multi-disciplinary journal that focuses on understanding the exposure and effects of environmental contamination on organisms including human health. The scope of the journal covers three main themes. The topics within these themes, indicated below, include (but are not limited to) the following: Ecotoxicology、Environmental Chemistry、Environmental Safety etc.
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