Unlocking body-surface physiological evolution via IR-temperature dual sensing with single chalcogenide fiber

IF 23.4 Q1 OPTICS Light-Science & Applications Pub Date : 2025-04-25 DOI:10.1038/s41377-025-01840-y

Yanqing Fu, Shiliang Kang, Gangjie Zhou, Xinxiang Huang, Linling Tan, Chengwei Gao, Shixun Dai, Changgui Lin

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Abstract

Improvements to body-surface physiological monitoring ability including real-time, accuracy and integration, are essential to meet the expansive demands for personal healthcare. As part of this, simultaneous monitoring of sweat metabolites and body temperature offers an exciting path to maximizing diagnostic precision and minimizing morbidity rates. Herein, we report a high-performance biomarker-temperature sensor made of a single As₃Se₅Te₂ chalcogenide glass fiber to monitor physiology evolution on body-surface. The sensor integrates efficient thermal resistance and fiber evanescent wave effects, permitting the independent sensing of temperature and biomarkers with an ultrahigh temperature coefficient of resistance (−5.84% K^–1), rapid temperature response (0.3 s) and excellent IR sensing sensitivity. Moreover, by attaching a fiber to the wrist, we demonstrate simultaneous observation of both sweat metabolite (urea and lactate) and temperature changes during exercise. This illuminating sensing method will provide crucial capabilities in physiological monitoring and pave the way for advanced personalized diagnostic.

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利用单硫族纤维红外-温度双传感解锁体表生理进化

提高体表生理监测能力，包括实时性、准确性和集成度，是满足个人医疗保健日益增长的需求所必需的。作为其中的一部分，同时监测汗液代谢物和体温为最大限度地提高诊断精度和降低发病率提供了一条令人兴奋的途径。在此，我们报道了一种高性能的生物标志物-温度传感器，该传感器由单个As3Se5Te2硫系玻璃纤维制成，用于监测体表生理进化。该传感器集成了高效的热阻和纤维倏逝波效应，允许独立感知温度和生物标志物，具有超高的温度电阻系数（−5.84% K-1），快速的温度响应（0.3 s）和出色的红外传感灵敏度。此外，通过在手腕上附着一根纤维，我们演示了在运动过程中同时观察汗液代谢物（尿素和乳酸）和温度变化。这种照明传感方法将为生理监测提供关键能力，并为先进的个性化诊断铺平道路。

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