{"title":"Malathion Lotion as an Insecticide and Ovicide in Head Louse Infestation","authors":"Francisco Gomez Urcuyo M.D., Nardo Zaias M.D.","doi":"10.1111/j.1365-4362.1986.tb03408.x","DOIUrl":null,"url":null,"abstract":"<p><b>ABSTRACT: </b> A lotion containing 0.5% malathion was compared with its vehicle (control) in a double-blind, parallel-group study of 119 patients with head louse infestations confirmed by live ova in the hair. The lotions remained in place for 8 hours. The test preparation was superior to the control lotion by a highly significant margin (p < 0.001) as determined by the numbers of patients with live lice at 24 hours and 7 days after removal of the respective materials. It also proved superior to the vehicle (p < 0.001) as an ovicidal agent, judged by comparative differences in hatching rates between nits collected and incubated before treatment and those obtained and incubated after treatment. No adverse reaction occurred.</p>","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":"25 1","pages":"60-62"},"PeriodicalIF":3.2000,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1365-4362.1986.tb03408.x","citationCount":"20","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Dermatology","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/j.1365-4362.1986.tb03408.x","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"DERMATOLOGY","Score":null,"Total":0}
引用次数: 20
Abstract
ABSTRACT: A lotion containing 0.5% malathion was compared with its vehicle (control) in a double-blind, parallel-group study of 119 patients with head louse infestations confirmed by live ova in the hair. The lotions remained in place for 8 hours. The test preparation was superior to the control lotion by a highly significant margin (p < 0.001) as determined by the numbers of patients with live lice at 24 hours and 7 days after removal of the respective materials. It also proved superior to the vehicle (p < 0.001) as an ovicidal agent, judged by comparative differences in hatching rates between nits collected and incubated before treatment and those obtained and incubated after treatment. No adverse reaction occurred.
期刊介绍:
Published monthly, the International Journal of Dermatology is specifically designed to provide dermatologists around the world with a regular, up-to-date source of information on all aspects of the diagnosis and management of skin diseases. Accepted articles regularly cover clinical trials; education; morphology; pharmacology and therapeutics; case reports, and reviews. Additional features include tropical medical reports, news, correspondence, proceedings and transactions, and education.
The International Journal of Dermatology is guided by a distinguished, international editorial board and emphasizes a global approach to continuing medical education for physicians and other providers of health care with a specific interest in problems relating to the skin.