{"title":"Initiation of ethanol-maintained responding using a schedule-induction procedure in free feeding rats.","authors":"H H Samson, A O Pfeffer","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>A schedule-induced adjunctive drinking procedure was used to initiate ethanol self-administration in free feeding rats. The rats were first trained on a FI 90-sec schedule with 20% sucrose reinforcement, and then ethanol was made concurrently available on a CRF schedule on a second lever. After 25 concurrent sessions, the sucrose was removed and the ethanol response requirement was brought to FR8. Finally, ethanol concentrations were varied up to 40%. Of 11 rats, 8 responded for sucrose on the FI 90 sec schedule, and 5 of those responded for 40% ethanol at FR8. These results were compared to previous studies using the same procedure in food-restricted rats and other procedures in free feeding rats. Possible explanations for the lower success using schedule induction in nondeprived rats were discussed.</p>","PeriodicalId":7671,"journal":{"name":"Alcohol and drug research","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1987-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Alcohol and drug research","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
A schedule-induced adjunctive drinking procedure was used to initiate ethanol self-administration in free feeding rats. The rats were first trained on a FI 90-sec schedule with 20% sucrose reinforcement, and then ethanol was made concurrently available on a CRF schedule on a second lever. After 25 concurrent sessions, the sucrose was removed and the ethanol response requirement was brought to FR8. Finally, ethanol concentrations were varied up to 40%. Of 11 rats, 8 responded for sucrose on the FI 90 sec schedule, and 5 of those responded for 40% ethanol at FR8. These results were compared to previous studies using the same procedure in food-restricted rats and other procedures in free feeding rats. Possible explanations for the lower success using schedule induction in nondeprived rats were discussed.
分享
京公网安备 11010802042870号
京ICP备2023020795号-1
求助内容：
应助结果提醒方式：
扫码关注我们
