Effect of UV-irradiation, spleen cells and MLN cells on protective immunity against Angiostrongylus cantonensis infection in mice.

V R Kamath, S Menon, D M Renapurkar
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引用次数: 2

Abstract

The UV-irradiated larvae of Angiostrongylus cantonensis were used for inducing immunity in mice. A single oral dose of 100 infective UV-irradiated larvae exposed for 5 min or 15 min induced 91% and 97% protection against subsequent infection. Adoptive protection against A. cantonensis could also be transferred by spleen and mesenteric lymph node cells obtained from vaccinated mice.

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紫外线照射、脾细胞和MLN细胞对小鼠抗广州管圆线虫感染保护性免疫的影响。
采用紫外线照射的广州管圆线虫幼虫对小鼠进行免疫诱导。单次口服100只受感染的紫外线照射的幼虫,暴露5分钟或15分钟,对后续感染的保护率分别为91%和97%。免疫小鼠的脾脏和肠系膜淋巴结细胞也能传递对广东弧菌的过继保护。
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