Heavy drinking decreases plasma met-enkephalin concentrations.

Alcohol and drug research Pub Date : 1987-01-01
S Govoni, G Pasinetti, A Bianchi, M Gadola, M Trabucchi
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Abstract

Plasma met-enkephalin immunoreactive material (ME-IR) concentration was measured in 175 aged subjects (68 males, 107 females). Heavy drinking (1 liter of red or white wine a day, equivalent roughly to greater than 110 g ethanol) was associated with reduced ME-IR concentrations. On the other hand, no correlation was found between plasma ME-IR and other parameters such as blood pressure, age or body weight. These data favor the hypothesis of an involvement of ME-IR in the mechanisms of ethanol action.

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大量饮酒可降低血浆脑啡肽浓度。
测定175例老年受试者(男性68例,女性107例)血浆met-enkephalin免疫反应物质(ME-IR)浓度。大量饮酒(每天1升红葡萄酒或白葡萄酒,大致相当于超过110克乙醇)与ME-IR浓度降低有关。另一方面,血浆ME-IR与血压、年龄或体重等其他参数之间没有相关性。这些数据支持ME-IR参与乙醇作用机制的假设。
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