Estimation of major immunoglobulin profile in oral submucous fibrosis by radial immunodiffusion

Dinesh S. Gupta , Mithileshkumar Gupta, Rajesh H. Oswal
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引用次数: 27

Abstract

Oral submucous fibrosis is defined as a collagen disease. The major immunoglobulin profile of 10 patients of oral submucous fibrosis (OSF) is estimated by radial immunodiffusion technique. The possible existence of autoimmune phenomena is expressed. It was observed in the present study that the severity of oral submucous fibrosis was directly proportional to the estimated elevated levels of major immunoglobulins. This may be taken as an indicator to know the gravity of this oral condition and also to evaluate the various related gammopathies and their possible management. It is anticipated that the knowledge of the immunoprofile would open new avenues for exploration of the condition from a new dimension.

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放射免疫扩散法估计口腔黏膜下纤维化的主要免疫球蛋白谱
口腔黏膜下纤维化被定义为一种胶原蛋白疾病。应用放射免疫扩散技术对10例口腔黏膜下纤维化(OSF)患者的主要免疫球蛋白谱进行了分析。表达了自身免疫现象的可能存在。在本研究中观察到,口腔粘膜下纤维化的严重程度与估计的主要免疫球蛋白水平升高成正比。这可以作为了解这种口腔疾病严重性的指标,也可以评估各种相关的伽玛病及其可能的治疗方法。预计免疫谱的知识将为从一个新的维度探索这种疾病开辟新的途径。
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