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A case of large cell neuroendocrine carcinoma of the tongue 舌大细胞神经内分泌癌1例
Pub Date : 2015-04-01 DOI: 10.5794/jjoms.61.212
Ryuta Osaka, I. Uchida, Sadao Oyama, H. Miyashita, S. Kawai, T. Shibahara
Large cell neuroendocrine carcinomas (LCNEC) are relatively rare tumors that arise in various organs. We report a case of primary LCNEC of the tongue. A 60-year-old man was referred to our department because of impaired swallowing function due to pain while eating, as well as an ulcer on the left side of the tongue. Squamous cell carcinoma was suspected on biopsy. A whole-body examination showed no evidence of metastasis. Therefore, the patient was given a clinical diagnosis of squamous cell carcinoma of the left side of the tongue suspected (cT4aN2bM0: Stage IVa). After preoperative chemotherapy, we performed a tracheostomy, bilateral neck dissection, complete removal of the tongue, and reconstructive surgery using a rectus abdominis free flap, with the patient under general anesthesia. Histologically, the tumor was composed of solid nests of atypical large cells. Necrosis was remarkable. Tumor nests showed peripheral palisading and rosette formation. Immunohistochemically, the cancer cells were positive for chromogranin A and synaptophysin. We diagnosed this tumor as LCNEC, based on the criteria established for pulmonary tumors. The patient is alive without recurrence or metastasis 55 months after surgery. Since LCNEC is exceptionally rare in the head and neck region, especially in the oral cavity, the prognosis was unclear, and treatment has not been established. Hence, studies of further cases are required to establish adequate treatment for LCNEC of the head and neck region.
大细胞神经内分泌癌(LCNEC)是一种发生在各种器官的相对罕见的肿瘤。我们报告一例原发性舌头LCNEC。一位60岁男性患者因进食时疼痛导致吞咽功能受损,并伴有左侧舌部溃疡而转介至我科。活检怀疑为鳞状细胞癌。全身检查未见转移迹象。因此,临床诊断疑似舌左侧鳞状细胞癌(cT4aN2bM0: IVa期)。术前化疗后,我们在全身麻醉下进行了气管切开、双侧颈部清扫、完全切除舌头和腹直肌游离皮瓣重建手术。组织学上,肿瘤由非典型大细胞组成的实巢。坏死明显。肿瘤巢外周呈栅栏状,呈玫瑰花结状。免疫组化结果显示,肿瘤细胞嗜铬粒蛋白A和突触素阳性。根据肺肿瘤的诊断标准,我们将该肿瘤诊断为LCNEC。患者术后55个月无复发或转移。由于LCNEC在头颈部特别罕见,尤其是在口腔,预后不明确,治疗方法尚未建立。因此,需要对更多的病例进行研究,以确定头颈部LCNEC的适当治疗方法。
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引用次数: 0
A case of epidermoid cyst arising in the left side of the root of the tongue 舌根左侧出现表皮样囊肿1例
Pub Date : 2015-01-01 DOI: 10.5794/jjoms.61.421
T. Fujii, Y. Ohnishi, Masahiro Watanabe, Yoshiha Oku, M. Wato, K. Kakudo
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引用次数: 0
Application of microendosurgery for extensive radicular cysts 显微内镜在广泛神经根性囊肿中的应用
Pub Date : 2015-01-01 DOI: 10.5794/jjoms.61.402
M. Ogawa, S. Yokoo
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引用次数: 0
A case of posterior open bite after bilateral coronoidectomy and aponeurectomy of the masseter muscles 双侧咬肌冠状切除术及腱神经切除术后开放性咬伤1例
Pub Date : 2015-01-01 DOI: 10.5794/jjoms.61.412
T. Kirisawa, Y. Moriya, Keiichi Morioka, Seibu Matsumoto
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引用次数: 1
Development of standards for stored autologous blood transfunction. Adaptation to orthognathic surgery.:Adaptation to orthognathic surgery 储存自体血功能异常标准的制定。适应正颌手术。:适应正颌手术
Pub Date : 1994-01-01 DOI: 10.5794/jjoms.40.665
Masashi Yoshida, K. Sugihara, H. Mukai, K. Kawashima, H. Kuniyoshi, S. Yamashita
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引用次数: 0
A clinical study of mandibular angle fractures, with special reference to treatment of wisdom teeth in the fracture line.:with special reference to treatment of wisdom teeth in the fracture line 下颌角骨折的临床研究,特别参考在骨折线上智齿的治疗。:特别参考智齿骨折线的治疗
Pub Date : 1993-06-20 DOI: 10.5794/JJOMS.39.762
M. Higa, M. Yamashiro, H. Sunakawa, T. Kinjo, H. Gima, A. Arasaki, K. Tsuhako, Manabu Kishaba, Munenori Ganaha, Yasutaka Yamashiro, S. Oshiro, W. Tsuhako, Keiichi Arakaki, N. Fujii
We have analysed 93 patients with mandibular angle fractures, with special re-ference to the treatment of wisdom teeth in the fracture line, during the past 6 years (1985-1990) at the Department of Oral Surgery, Ryukyu University Hospital.The results were as follows:1) Among 97 fracture lines in 93 cases, there were 89 wisdom teeth (91. 8%) and 31 of these were extracted.2) Erupted teeth tended to be extracted, while premature teeth tended to be preserved.3) There were few differences in prognosis of fractures between preserved cases and ex-tracted cases. These results suggest that the treatment of wisdom teeth should be consideedon an individual basis.
我们分析了过去6年间(1985-1990)在琉球大学医院口腔外科治疗的93例下颌角骨折患者,特别参考了骨折线上智齿的治疗。结果表明:1)93例患者97条骨折线中,智齿89颗(91颗);2)萌牙倾向于拔除,早牙倾向于保留。3)保留病例与拔除病例骨折预后差异不大。这些结果表明,智齿的治疗应考虑到个人的基础上。
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引用次数: 0
A case of verruciform xanthoma of the gingiva on upper jaw. With immunochemical and ultrastructural observation.:with immmochemical and ultrastructural observation 上颌牙龈疣状黄色瘤1例。结合免疫化学和超微结构观察。免疫化学和超微结构观察
Pub Date : 1990-11-20 DOI: 10.5794/JJOMS.36.2544
M. Mishina, Ryuichi Nemoto, Michio Furuta, T. Ohno
Verruciform xanthoma arising from the gingival mucosa of the upper left first premolar to first molar area of a 59-year-old female is presented. It is a rare lesion of the oral cavity which has a warty or papillary appearance. It was first described by Shafer in 1971 with histopathological characteristics of verruciform growth and proliferation of xanthoma cells in the lamina propia.In Japan Kikuchi et al. reported the first case in 1977. Since then almost 40 cases have so far been published.This article described a case of Verruciform xanthoma together with its light, immunochemical and and electron microscopic fingings. Judging from the immunochemical finding, foamy cells were negative for S-100 protein and positive for lysozyme and NCA (non-specific cross reacting antigen with carcinoembryonic antigen), all of which were suggested that they were derived from monocyte-macrophage cell lines.
本文报告一59岁女性左上第一前磨牙至第一磨牙牙龈黏膜疣状黄色瘤。这是一种罕见的口腔病变,有疣状或乳头状外观。Shafer于1971年首次描述了这种疾病,其组织病理学特征是在耳膜中出现疣状生长和黄色瘤细胞增殖。在日本,Kikuchi等人于1977年报告了首例病例。从那时起,到目前为止已经发表了近40个病例。本文报告1例疣状黄色瘤及其光镜、免疫化学和电镜指征。免疫化学结果显示,泡沫细胞S-100蛋白呈阴性,溶菌酶和NCA(非特异性癌胚交叉反应抗原)呈阳性,提示泡沫细胞来源于单核-巨噬细胞系。
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引用次数: 0
Experimental studies of the influence of mandible resection and effects of its reconstruction on the growth of the mandible. 2. Effects of reconstruction of mandibular bone defects.:2. Effects of reconstruction of mandibular bone defects 下颌骨切除及重建对下颌骨生长影响的实验研究。2. 下颌骨缺损的修复效果[j]。下颌骨缺损的修复效果
Pub Date : 1990-01-01 DOI: 10.5794/JJOMS.36.841
Koichi Yamamoto
Bone defects in the growing period give rise to mandibular growth obstruction. After the bone is resected, the defect in the mandible is reconstructed by means of bone graft or ceramic implantation to maintain mandible form and function, but the effect on mandibular growth has not been studied in detail. So the author has studied experimentally the effects of bone graft and the implantation of 2 types of ceramics, hydroxylapatite (HA) and tricarcium phosphate (TCP), in surgically caused mandible defects growth.Ninety-six 4-week-old WKA rats were used in this study. Of these 36 rats were used for histological study and 60 were divided equally into the 6 following groups: Group 1. Bone was grafted into the defect at the mandibular body inferior border. Group 2. Bone was grafted into the defect at the mandibular ramus center. Group 3. Fibrin adhesion system (Tisseel ® kit) was filled into the bone defect created the same as in group 1. Group 4. Bone was grafted with fibrin adhesion system into the bone defect created the same as in group 1. Group 5. HA was implanted with fibrin adhesion system into the bone defect created the same as in group 1. Group 6. TCP was implanted with fibrin adhesion system into the defect created the same as in group 1. Sixty of the rats were sacrified at 15 weeks of age, decapitated, and the obtained specimens were evaluated by measurement, contact microradiography and radiography.Growth inhibition of the mandible after resection of the mandible inferior border was significantly improved by replantation of the removed bone itself to the resected site, but there was no significant effect on mandible growth when the defect at the mandibular ramus center was filled with bone. Ceramics implantation into the defect of the mandible inferior border showed a similar but not significant effect to that seen in the case of bone replantation.
生长时期的骨缺损会造成下颌生长障碍。骨切除后,通过骨移植或陶瓷种植重建下颌骨缺损,维持下颌骨形态和功能,但对下颌骨生长的影响尚未有详细的研究。因此,笔者对羟基磷灰石(HA)和磷酸三钙(TCP)两种陶瓷在手术所致下颌骨缺损生长中的作用进行了实验研究。本研究选用96只4周龄WKA大鼠。取36只大鼠进行组织学研究,60只平均分为以下6组:第一组;骨移植于下颌骨体下缘缺损处。组2。将骨移植到下颌支中心的缺损处。组3。将纤维蛋白粘连系统(Tisseel®kit)填充到与1组相同的骨缺损中。组4。采用纤维蛋白黏附系统将骨移植到与1组相同的骨缺损处。5组。将透明质酸与纤维蛋白黏附系统植入与1组相同的骨缺损。6组。与1组相同,将纤维蛋白黏附系统植入TCP。15周龄处死60只大鼠,取其头颅,用测量法、接触显微放射照相法和放射线照相法对所得标本进行评价。下颌骨下缘切除后,将切除的骨本身再植于切除部位,可明显改善下颌骨生长抑制,但在下颌分支中心缺损处填充骨对下颌骨生长无明显影响。下颌骨下缘缺损的陶瓷植入效果与骨再植相似,但效果不显著。
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引用次数: 0
An experimental study on implantation of HAP-ZOE complex in jaw bone. Physical and chemical properties.:Physical and chemical properties HAP-ZOE复合物颌骨植入的实验研究。物理和化学性质。物理和化学性质
Pub Date : 1990-01-01 DOI: 10.5794/JJOMS.36.268
H. Umeda
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引用次数: 0
Biomechanical study of static pressure on facial bone fractures. Part I. Strain distribution under static loads.:Part I Strain Distribution under static Loads 面骨骨折静压的生物力学研究。第一部分:静载荷下的应变分布。:第一部分静载荷下的应变分布
Pub Date : 1987-01-01 DOI: 10.5794/JJOMS.33.1932
Yuetsu Onoe, N. Maeda, T. Ishikawa, Kousuke Honda, W. Yoshioka, S. Tsutsumi
To achieve a complete under-standing of the biomechanical aspects involved when maxillofacial bones are stricken by external forces, it is necessary to study them as one body. Experiments carried out following this concept are reported here. Different weights were applied to the mandible at the center of the mental region and the distribution of principal strains of bone were analyzed.It was found that force is transmitted through the mandibular bone along the bone radial structure. On the maxillofacial bone, the zygomatic arch received most of the stresses and suffered frequent damage.
为了全面了解颌面骨受外力冲击时所涉及的生物力学方面,有必要将颌面骨作为一个整体来研究。这里报告了根据这一概念进行的实验。对颏区中心的下颌骨施加不同的权重,分析骨主应变的分布。我们发现力是沿着骨径向结构通过下颌骨传递的。在颌面骨上,颧弓承受的应力最大,损伤频繁。
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International journal of oral surgery
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