Ryuta Osaka, I. Uchida, Sadao Oyama, H. Miyashita, S. Kawai, T. Shibahara
Large cell neuroendocrine carcinomas (LCNEC) are relatively rare tumors that arise in various organs. We report a case of primary LCNEC of the tongue. A 60-year-old man was referred to our department because of impaired swallowing function due to pain while eating, as well as an ulcer on the left side of the tongue. Squamous cell carcinoma was suspected on biopsy. A whole-body examination showed no evidence of metastasis. Therefore, the patient was given a clinical diagnosis of squamous cell carcinoma of the left side of the tongue suspected (cT4aN2bM0: Stage IVa). After preoperative chemotherapy, we performed a tracheostomy, bilateral neck dissection, complete removal of the tongue, and reconstructive surgery using a rectus abdominis free flap, with the patient under general anesthesia. Histologically, the tumor was composed of solid nests of atypical large cells. Necrosis was remarkable. Tumor nests showed peripheral palisading and rosette formation. Immunohistochemically, the cancer cells were positive for chromogranin A and synaptophysin. We diagnosed this tumor as LCNEC, based on the criteria established for pulmonary tumors. The patient is alive without recurrence or metastasis 55 months after surgery. Since LCNEC is exceptionally rare in the head and neck region, especially in the oral cavity, the prognosis was unclear, and treatment has not been established. Hence, studies of further cases are required to establish adequate treatment for LCNEC of the head and neck region.
{"title":"A case of large cell neuroendocrine carcinoma of the tongue","authors":"Ryuta Osaka, I. Uchida, Sadao Oyama, H. Miyashita, S. Kawai, T. Shibahara","doi":"10.5794/jjoms.61.212","DOIUrl":"https://doi.org/10.5794/jjoms.61.212","url":null,"abstract":"Large cell neuroendocrine carcinomas (LCNEC) are relatively rare tumors that arise in various organs. We report a case of primary LCNEC of the tongue. A 60-year-old man was referred to our department because of impaired swallowing function due to pain while eating, as well as an ulcer on the left side of the tongue. Squamous cell carcinoma was suspected on biopsy. A whole-body examination showed no evidence of metastasis. Therefore, the patient was given a clinical diagnosis of squamous cell carcinoma of the left side of the tongue suspected (cT4aN2bM0: Stage IVa). After preoperative chemotherapy, we performed a tracheostomy, bilateral neck dissection, complete removal of the tongue, and reconstructive surgery using a rectus abdominis free flap, with the patient under general anesthesia. Histologically, the tumor was composed of solid nests of atypical large cells. Necrosis was remarkable. Tumor nests showed peripheral palisading and rosette formation. Immunohistochemically, the cancer cells were positive for chromogranin A and synaptophysin. We diagnosed this tumor as LCNEC, based on the criteria established for pulmonary tumors. The patient is alive without recurrence or metastasis 55 months after surgery. Since LCNEC is exceptionally rare in the head and neck region, especially in the oral cavity, the prognosis was unclear, and treatment has not been established. Hence, studies of further cases are required to establish adequate treatment for LCNEC of the head and neck region.","PeriodicalId":14224,"journal":{"name":"International journal of oral surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73198897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Fujii, Y. Ohnishi, Masahiro Watanabe, Yoshiha Oku, M. Wato, K. Kakudo
{"title":"A case of epidermoid cyst arising in the left side of the root of the tongue","authors":"T. Fujii, Y. Ohnishi, Masahiro Watanabe, Yoshiha Oku, M. Wato, K. Kakudo","doi":"10.5794/jjoms.61.421","DOIUrl":"https://doi.org/10.5794/jjoms.61.421","url":null,"abstract":"","PeriodicalId":14224,"journal":{"name":"International journal of oral surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79723884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Application of microendosurgery for extensive radicular cysts","authors":"M. Ogawa, S. Yokoo","doi":"10.5794/jjoms.61.402","DOIUrl":"https://doi.org/10.5794/jjoms.61.402","url":null,"abstract":"","PeriodicalId":14224,"journal":{"name":"International journal of oral surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79068090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Kirisawa, Y. Moriya, Keiichi Morioka, Seibu Matsumoto
{"title":"A case of posterior open bite after bilateral coronoidectomy and aponeurectomy of the masseter muscles","authors":"T. Kirisawa, Y. Moriya, Keiichi Morioka, Seibu Matsumoto","doi":"10.5794/jjoms.61.412","DOIUrl":"https://doi.org/10.5794/jjoms.61.412","url":null,"abstract":"","PeriodicalId":14224,"journal":{"name":"International journal of oral surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85324421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Masashi Yoshida, K. Sugihara, H. Mukai, K. Kawashima, H. Kuniyoshi, S. Yamashita
{"title":"Development of standards for stored autologous blood transfunction. Adaptation to orthognathic surgery.:Adaptation to orthognathic surgery","authors":"Masashi Yoshida, K. Sugihara, H. Mukai, K. Kawashima, H. Kuniyoshi, S. Yamashita","doi":"10.5794/jjoms.40.665","DOIUrl":"https://doi.org/10.5794/jjoms.40.665","url":null,"abstract":"","PeriodicalId":14224,"journal":{"name":"International journal of oral surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72868316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Higa, M. Yamashiro, H. Sunakawa, T. Kinjo, H. Gima, A. Arasaki, K. Tsuhako, Manabu Kishaba, Munenori Ganaha, Yasutaka Yamashiro, S. Oshiro, W. Tsuhako, Keiichi Arakaki, N. Fujii
We have analysed 93 patients with mandibular angle fractures, with special re-ference to the treatment of wisdom teeth in the fracture line, during the past 6 years (1985-1990) at the Department of Oral Surgery, Ryukyu University Hospital.The results were as follows:1) Among 97 fracture lines in 93 cases, there were 89 wisdom teeth (91. 8%) and 31 of these were extracted.2) Erupted teeth tended to be extracted, while premature teeth tended to be preserved.3) There were few differences in prognosis of fractures between preserved cases and ex-tracted cases. These results suggest that the treatment of wisdom teeth should be consideedon an individual basis.
{"title":"A clinical study of mandibular angle fractures, with special reference to treatment of wisdom teeth in the fracture line.:with special reference to treatment of wisdom teeth in the fracture line","authors":"M. Higa, M. Yamashiro, H. Sunakawa, T. Kinjo, H. Gima, A. Arasaki, K. Tsuhako, Manabu Kishaba, Munenori Ganaha, Yasutaka Yamashiro, S. Oshiro, W. Tsuhako, Keiichi Arakaki, N. Fujii","doi":"10.5794/JJOMS.39.762","DOIUrl":"https://doi.org/10.5794/JJOMS.39.762","url":null,"abstract":"We have analysed 93 patients with mandibular angle fractures, with special re-ference to the treatment of wisdom teeth in the fracture line, during the past 6 years (1985-1990) at the Department of Oral Surgery, Ryukyu University Hospital.The results were as follows:1) Among 97 fracture lines in 93 cases, there were 89 wisdom teeth (91. 8%) and 31 of these were extracted.2) Erupted teeth tended to be extracted, while premature teeth tended to be preserved.3) There were few differences in prognosis of fractures between preserved cases and ex-tracted cases. These results suggest that the treatment of wisdom teeth should be consideedon an individual basis.","PeriodicalId":14224,"journal":{"name":"International journal of oral surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1993-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77718595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Mishina, Ryuichi Nemoto, Michio Furuta, T. Ohno
Verruciform xanthoma arising from the gingival mucosa of the upper left first premolar to first molar area of a 59-year-old female is presented. It is a rare lesion of the oral cavity which has a warty or papillary appearance. It was first described by Shafer in 1971 with histopathological characteristics of verruciform growth and proliferation of xanthoma cells in the lamina propia.In Japan Kikuchi et al. reported the first case in 1977. Since then almost 40 cases have so far been published.This article described a case of Verruciform xanthoma together with its light, immunochemical and and electron microscopic fingings. Judging from the immunochemical finding, foamy cells were negative for S-100 protein and positive for lysozyme and NCA (non-specific cross reacting antigen with carcinoembryonic antigen), all of which were suggested that they were derived from monocyte-macrophage cell lines.
{"title":"A case of verruciform xanthoma of the gingiva on upper jaw. With immunochemical and ultrastructural observation.:with immmochemical and ultrastructural observation","authors":"M. Mishina, Ryuichi Nemoto, Michio Furuta, T. Ohno","doi":"10.5794/JJOMS.36.2544","DOIUrl":"https://doi.org/10.5794/JJOMS.36.2544","url":null,"abstract":"Verruciform xanthoma arising from the gingival mucosa of the upper left first premolar to first molar area of a 59-year-old female is presented. It is a rare lesion of the oral cavity which has a warty or papillary appearance. It was first described by Shafer in 1971 with histopathological characteristics of verruciform growth and proliferation of xanthoma cells in the lamina propia.In Japan Kikuchi et al. reported the first case in 1977. Since then almost 40 cases have so far been published.This article described a case of Verruciform xanthoma together with its light, immunochemical and and electron microscopic fingings. Judging from the immunochemical finding, foamy cells were negative for S-100 protein and positive for lysozyme and NCA (non-specific cross reacting antigen with carcinoembryonic antigen), all of which were suggested that they were derived from monocyte-macrophage cell lines.","PeriodicalId":14224,"journal":{"name":"International journal of oral surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1990-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80850427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bone defects in the growing period give rise to mandibular growth obstruction. After the bone is resected, the defect in the mandible is reconstructed by means of bone graft or ceramic implantation to maintain mandible form and function, but the effect on mandibular growth has not been studied in detail. So the author has studied experimentally the effects of bone graft and the implantation of 2 types of ceramics, hydroxylapatite (HA) and tricarcium phosphate (TCP), in surgically caused mandible defects growth.Ninety-six 4-week-old WKA rats were used in this study. Of these 36 rats were used for histological study and 60 were divided equally into the 6 following groups: Group 1. Bone was grafted into the defect at the mandibular body inferior border. Group 2. Bone was grafted into the defect at the mandibular ramus center. Group 3. Fibrin adhesion system (Tisseel ® kit) was filled into the bone defect created the same as in group 1. Group 4. Bone was grafted with fibrin adhesion system into the bone defect created the same as in group 1. Group 5. HA was implanted with fibrin adhesion system into the bone defect created the same as in group 1. Group 6. TCP was implanted with fibrin adhesion system into the defect created the same as in group 1. Sixty of the rats were sacrified at 15 weeks of age, decapitated, and the obtained specimens were evaluated by measurement, contact microradiography and radiography.Growth inhibition of the mandible after resection of the mandible inferior border was significantly improved by replantation of the removed bone itself to the resected site, but there was no significant effect on mandible growth when the defect at the mandibular ramus center was filled with bone. Ceramics implantation into the defect of the mandible inferior border showed a similar but not significant effect to that seen in the case of bone replantation.
{"title":"Experimental studies of the influence of mandible resection and effects of its reconstruction on the growth of the mandible. 2. Effects of reconstruction of mandibular bone defects.:2. Effects of reconstruction of mandibular bone defects","authors":"Koichi Yamamoto","doi":"10.5794/JJOMS.36.841","DOIUrl":"https://doi.org/10.5794/JJOMS.36.841","url":null,"abstract":"Bone defects in the growing period give rise to mandibular growth obstruction. After the bone is resected, the defect in the mandible is reconstructed by means of bone graft or ceramic implantation to maintain mandible form and function, but the effect on mandibular growth has not been studied in detail. So the author has studied experimentally the effects of bone graft and the implantation of 2 types of ceramics, hydroxylapatite (HA) and tricarcium phosphate (TCP), in surgically caused mandible defects growth.Ninety-six 4-week-old WKA rats were used in this study. Of these 36 rats were used for histological study and 60 were divided equally into the 6 following groups: Group 1. Bone was grafted into the defect at the mandibular body inferior border. Group 2. Bone was grafted into the defect at the mandibular ramus center. Group 3. Fibrin adhesion system (Tisseel ® kit) was filled into the bone defect created the same as in group 1. Group 4. Bone was grafted with fibrin adhesion system into the bone defect created the same as in group 1. Group 5. HA was implanted with fibrin adhesion system into the bone defect created the same as in group 1. Group 6. TCP was implanted with fibrin adhesion system into the defect created the same as in group 1. Sixty of the rats were sacrified at 15 weeks of age, decapitated, and the obtained specimens were evaluated by measurement, contact microradiography and radiography.Growth inhibition of the mandible after resection of the mandible inferior border was significantly improved by replantation of the removed bone itself to the resected site, but there was no significant effect on mandible growth when the defect at the mandibular ramus center was filled with bone. Ceramics implantation into the defect of the mandible inferior border showed a similar but not significant effect to that seen in the case of bone replantation.","PeriodicalId":14224,"journal":{"name":"International journal of oral surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89660222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An experimental study on implantation of HAP-ZOE complex in jaw bone. Physical and chemical properties.:Physical and chemical properties","authors":"H. Umeda","doi":"10.5794/JJOMS.36.268","DOIUrl":"https://doi.org/10.5794/JJOMS.36.268","url":null,"abstract":"","PeriodicalId":14224,"journal":{"name":"International journal of oral surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82591644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yuetsu Onoe, N. Maeda, T. Ishikawa, Kousuke Honda, W. Yoshioka, S. Tsutsumi
To achieve a complete under-standing of the biomechanical aspects involved when maxillofacial bones are stricken by external forces, it is necessary to study them as one body. Experiments carried out following this concept are reported here. Different weights were applied to the mandible at the center of the mental region and the distribution of principal strains of bone were analyzed.It was found that force is transmitted through the mandibular bone along the bone radial structure. On the maxillofacial bone, the zygomatic arch received most of the stresses and suffered frequent damage.
{"title":"Biomechanical study of static pressure on facial bone fractures. Part I. Strain distribution under static loads.:Part I Strain Distribution under static Loads","authors":"Yuetsu Onoe, N. Maeda, T. Ishikawa, Kousuke Honda, W. Yoshioka, S. Tsutsumi","doi":"10.5794/JJOMS.33.1932","DOIUrl":"https://doi.org/10.5794/JJOMS.33.1932","url":null,"abstract":"To achieve a complete under-standing of the biomechanical aspects involved when maxillofacial bones are stricken by external forces, it is necessary to study them as one body. Experiments carried out following this concept are reported here. Different weights were applied to the mandible at the center of the mental region and the distribution of principal strains of bone were analyzed.It was found that force is transmitted through the mandibular bone along the bone radial structure. On the maxillofacial bone, the zygomatic arch received most of the stresses and suffered frequent damage.","PeriodicalId":14224,"journal":{"name":"International journal of oral surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1987-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89415336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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