G Arcaya, M E Pantoja, M Pieber, C Romero, J C Tohá
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引用次数: 7
Abstract
The interaction of L-aromatic aminoacids with bases and nucleosides is described. Of these, ʟ-tryptophan interacts more strongly with bases and nucleosides as indicated by nuclear magnetic resonance, circular dichroism and solubility measurements. A possible ring-ring type interaction between the aminoacid and bases or nucleosides is proposed; this interaction being such that the hydrodinamic behaviour of the DNA molecule is unchanged. Ultra violet irradiated DNA is protected by ʟ-tryptophan. A mechanism of energy transfer from the DNA to tryptophan trough triplet-triplet states is discussed.
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