[Tolerance of group A streptococci to the bactericidal effect of various antibiotics].

Antibiotiki Pub Date : 1984-12-01
N I Givental', O A Krasil'nikova, L F Bogdanova, L S Vorob'eva, A S Labinskaia
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Abstract

The MICs and MBCs (minimum bactericidal concentration) of 6 antibiotics (benzylpenicillin, oxacillin, cephalothin, ristomycin, erythromycin and lincomycin) for 50 strains of group A streptococci were determined with serial dilutions in a liquid medium (the medium for isolation of streptococci of the I. I. Mechnikov Moscow Research Institute of Vaccines and Sera) followed by volumetric platings on a solid medium (the same medium supplemented with 1.5 per cent agar). The results are discussed in relation to the problem of Streptococci tolerance to the bactericidal effect of the antibiotics.

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[A群链球菌对各种抗生素杀菌作用的耐受性]。
在液体培养基(ⅰ。ⅰ。梅奇尼科夫莫斯科疫苗和血清研究所用于分离链球菌的培养基)中连续稀释,然后在固体培养基(同样的培养基中添加1.5%的琼脂)上进行容量涂片,测定了50株A组链球菌的6种抗生素(青霉素、苯氧西林、头孢菌素、瑞霉素、红霉素和林可霉素)的mic和MBCs(最低杀菌浓度)。并就链球菌对抗生素杀菌作用的耐受问题进行了讨论。
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[Tolerance of group A streptococci to the bactericidal effect of various antibiotics]. [Oleandomycin content of mycelium and fermentation solution during cultivation of Streptomyces antibioticus]. [Polyresistant Enterobacteriaceae strains and their plasmids in a hospital. Medical and theoretical aspects]. [Methods of determining the sensitivity of anaerobic bacteria to antibacterial drugs]. [Structure of the antibiotic virenomycin].
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