P. Bentvelzen , F. Westenbrink , J.J. Broerse , M.J. Van Zwieten
{"title":"Absence of antigens related to murine mammary tumour virus polypeptides in rat mammary tumours","authors":"P. Bentvelzen , F. Westenbrink , J.J. Broerse , M.J. Van Zwieten","doi":"10.1016/0014-2964(81)90249-8","DOIUrl":null,"url":null,"abstract":"<div><p>Fifty-two rat mammary tumours were tested by radioimmunoassay for the presence of antigens related to the envelope glycoprotein gp<em>52</em> and core protein p<em>28</em> of the murine mammary tumour virus and found to be negative. The tumours assayed were from WAG/Rij (<em>16</em> cases), BN/BiRij (<em>16</em> cases) and Sprague—Dawley (<em>20</em> cases) rats. Thirty of the rats had been irradiated with fast neutrons, <em>16</em> with X-rays, one had been implanted with a <em>17</em>-β-oestradiol pellet and <em>5</em> were untreated. The tumours studied included <em>22</em> fibroadenomas, <em>2</em> adenomas, <em>19</em> adenocarcinomas, <em>4</em> sarcomas, <em>1</em> carcinosarcoma, and <em>4</em> of undetermined type.</p></div>","PeriodicalId":100497,"journal":{"name":"European Journal of Cancer (1965)","volume":"17 4","pages":"Pages 407-410"},"PeriodicalIF":0.0000,"publicationDate":"1981-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0014-2964(81)90249-8","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"European Journal of Cancer (1965)","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/0014296481902498","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 3
Abstract
Fifty-two rat mammary tumours were tested by radioimmunoassay for the presence of antigens related to the envelope glycoprotein gp52 and core protein p28 of the murine mammary tumour virus and found to be negative. The tumours assayed were from WAG/Rij (16 cases), BN/BiRij (16 cases) and Sprague—Dawley (20 cases) rats. Thirty of the rats had been irradiated with fast neutrons, 16 with X-rays, one had been implanted with a 17-β-oestradiol pellet and 5 were untreated. The tumours studied included 22 fibroadenomas, 2 adenomas, 19 adenocarcinomas, 4 sarcomas, 1 carcinosarcoma, and 4 of undetermined type.
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