Morphogenetic effect of cAMP during the metamorphosis of the frog larva.

G Csaba, A Szalkó, E Kapa
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Abstract

In an in vitro system, the tail absorption of the frog larva was significantly stimulated by cAMP more intensely than by T3. Theophylline, an inhibitor of cPDE, had no effect and failed to enhance, even decreased the effect of T3. It may be supposed that T3 does not act through a cAMP mechanism, but the tail absorption can be influenced by cAMP in a direct way.

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cAMP在蛙幼虫蜕变过程中的形态发生作用。
在体外系统中,cAMP比T3更强烈地刺激了蛙幼虫的尾部吸收。而cPDE抑制剂茶碱对T3没有作用,甚至没有增强甚至降低作用。可以推测T3不通过cAMP机制起作用,但cAMP可以直接影响其尾部吸收。
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