Prospective study of Epstein Barr virus (EBV) infection during pregnancy.

J Icart, J Didier, M Dalens, G Chabanon, A Boucays
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引用次数: 0

Abstract

The serological EBV profile of 2752 pregnant women characterized in most cases a latent EBV carrier state. The pregnancy rarely reactived this latent infection. But mothers with an "active" EBV serology gave birth more frequently than others to still born or defective bodies. In six pregnancies with primary EBV infection, detected early, four presented a pathological delivery. Furthermore the follow up of the EBV profile in 719 mothers revealed a significant relation between defective births and persistent EA antibodies. The role of EBV has yet to be precisely defined but the early detection of anti-EA EBV antibodies should be considered as a risk indicator in the management of pregnancy.

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妊娠期eb病毒(EBV)感染的前瞻性研究
2752例孕妇的EBV血清学特征,多数为潜伏型EBV携带者。妊娠很少会对这种潜伏感染产生反应。但EBV血清学“活跃”的母亲比其他母亲更容易生出死胎或有缺陷的婴儿。在6例早期发现的原发性EBV感染妊娠中,4例出现病理性分娩。此外,对719名母亲的EBV谱的随访显示,缺陷出生与持久性EA抗体之间存在显著关系。EBV的作用尚未得到精确的定义,但抗ea EBV抗体的早期检测应被视为妊娠管理的风险指标。
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