{"title":"[Alternative complement pathway].","authors":"M H Jouvin, M Kazatchkine","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The alternative complement pathway comprises three component proteins C3, B, D and three regulatory proteins P, H and I. These plasma proteins represent the major humoral defense mechanism against infection in a non-immune host. The following topics are reviewed: biochemistry of the alternative pathway proteins; molecular mechanisms of activation and regulation of the pathway; involvement of the alternative pathway in human diseases.</p>","PeriodicalId":18005,"journal":{"name":"La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris","volume":"60 19","pages":"1371-8"},"PeriodicalIF":0.0000,"publicationDate":"1984-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The alternative complement pathway comprises three component proteins C3, B, D and three regulatory proteins P, H and I. These plasma proteins represent the major humoral defense mechanism against infection in a non-immune host. The following topics are reviewed: biochemistry of the alternative pathway proteins; molecular mechanisms of activation and regulation of the pathway; involvement of the alternative pathway in human diseases.
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