Surgical and visual results of pediatric epikeratophakia.

K S Morgan, P A Asbell, J G May, M B McDonald, D N Loupe, H E Kaufman
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Abstract

We performed epikeratophakia for the correction of aphakia in 31 children, ages 2 months to 7 years, who had unilateral congenital or traumatic cataracts. In 27 patients with more than 4 months of follow-up, 23 of 30 (77%) grafts were successful. In the 15 patients with 6 months or more followup, the average increase in corneal curvature was 12.39 diopters. The average overrefraction needed to achieve emmetropia was + 2.14 diopters spherical equivalent. Two patients operated on within the first year of life have achieved 6/15 (20/50) visual acuities, as measured by visual evoked potentials. One patient operated on in the second year of life achieved 5/30 visual acuity, as measured by Allen cards. Two patients operated on for traumatic cataracts at ages 2 and 4 years achieved 6/9 (20/30) and 8/30 (Allen cards) visual acuities, respectively. Five older patients who had congenital cataracts or persistent hyperplastic vitreous showed some improvement in visual function. Advantages of epikeratophakia include the placement of most of the correction directly on the eye in a permanent attachment and the elimination of contact lens manipulation in uncooperative patients, so that more time and energy can be devoted to the occlusion therapy.

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小儿外角膜脱落的手术及目视结果。
我们对31例患有单侧先天性或外伤性白内障的2个月至7岁儿童进行了外角膜晶状体矫正术。在27例随访超过4个月的患者中,30例移植中有23例(77%)成功。随访6个月及以上的15例患者,角膜曲率平均增加12.39屈光度。达到远视所需的平均过折射为+ 2.14屈光度球面等效。通过视觉诱发电位测量,两名在出生后一年内接受手术的患者视力达到6/15(20/50)。一名患者在生命的第二年接受手术,通过艾伦卡片测量视力达到5/30。2例2岁和4岁外伤性白内障手术患者视力分别达到6/9(20/30)和8/30 (Allen卡)。5例有先天性白内障或持续性玻璃体增生的老年患者视功能有一定改善。外角膜晶状体的优点是大部分矫正物以永久附着体的形式直接放置在眼睛上,不配合的患者无需操作隐形眼镜,可以将更多的时间和精力用于遮挡治疗。
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Introductory comments for session V "neovasculogenesis" presented at the fifth symposium, the International Society on Metabolic Eye Disease October 24-26, 1982. Erythrocyte membrane 2', 3'-cyclic nucleotide 3'-phosphodiesterase activity in multiple sclerosis. Aspirin and prostacyclin treatment of diabetic dogs. Surgical and visual results of pediatric epikeratophakia. Prostaglandins in ocular pathophysiology with special reference to diabetic retinopathy and glaucoma.
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