[The effect of long-term plasmapheresis on the composition of blood. III. Changes in the concentration of total, direct and indirect bilirubin, alkaline phosphatase, serum transaminases (SGOT, SGPT). total lipids, triglycerides and cholesterol].

Abstract

In the group of blood donors submitted to the long term plasmapheresis with the weekly withdrawal of 370--670 ml of plasma, the concentrations of total bilirubin, alkaline phosphatase, aspartate (GOT) and alanine (GPT) transaminases, total lipids, triglycerides and cholesterol were not significantly changed (P greater than 0,05). The mean concentration of total lipids in plasma donors were close to the upper normal limit, while the concentrations of triglycerides slightly increased simultaneously with the increase of the number of plasmapheresis. The mean concentrations of indirect bilirubin significantly decreased (P less than 0,05) and the concentrations of indirect bilirubin increased (P less than 0,05), but because they do not differ significantly from the concentrations of the control group, these changes are of no clinical importance.