{"title":"Quantitative analysis of plasminogen activator in small arteries by modified fibrin plates.","authors":"G R Jacobs, J F Reinisch, C L Puckett","doi":"10.1002/micr.1920030304","DOIUrl":null,"url":null,"abstract":"The assay of plasminogen activator at the intimal surfaces of arteries less than 2 mm in diameter is possible using streptokinase‐ treated fibrin plates. Femoral arteries obtained from rats showed a reproducible fibrinolysis at their intimal surfaces that could be quantitated for the analysis of plasminogen activator. Utilization of the assay adjusted to the experimental situation would give a method of evaluating changes in the concentration of plasminogen activator at the intimal surface of small arteries when studied under various research conditions.","PeriodicalId":79226,"journal":{"name":"Journal of microsurgery","volume":"3 3","pages":"147-50"},"PeriodicalIF":0.0000,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/micr.1920030304","citationCount":"7","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of microsurgery","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1002/micr.1920030304","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 7
Abstract
The assay of plasminogen activator at the intimal surfaces of arteries less than 2 mm in diameter is possible using streptokinase‐ treated fibrin plates. Femoral arteries obtained from rats showed a reproducible fibrinolysis at their intimal surfaces that could be quantitated for the analysis of plasminogen activator. Utilization of the assay adjusted to the experimental situation would give a method of evaluating changes in the concentration of plasminogen activator at the intimal surface of small arteries when studied under various research conditions.
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