Jiayin Liu , Mengfan Yang , Jialing Tan , Yunjie Yin , Yongqiang Yang , Chaoxia Wang
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引用次数: 6
Abstract
Smart color-changing films are emerging as promising functional materials having multiple applications. pH-responsive discoloration film can present optical response to outer pH value, which has diverse functions like indicating, packaging and monitoring, etc. Prodigiosin possesses biodegradability and biocompatibility, which is a natural red pigment derived primarily from secondary metabolites of microorganisms. Based on these properties, an effective approach to develop pH-responsive discoloration film with biodegradability is proposed. Prodigiosins from microbial fermentation were evenly dispersed in silk fibroin solution to form a well-developed composite film via the casting method, exhibiting switchable pH-responsive color-changing performance. The film showed reddish-purple (λ max = 530 nm) at pH below 8, and turned to orange and yellow (λ max = 480 nm) as the pH increased from 8 to 10. The glycerol and 1-(3-Dimethylaminopropyl)-3-ethyl carbodiimide hydro (EDC) were incorporated as plasticizing and cross-linking agents, respectively. Glycerol and EDC significantly reduced the water contact angle from 83.4° to 4.7°and improved the mechanical properties of pH-responsive silk fibroin film. In addition, this pH-responsive silk fibroin-based film is biodegradable and can be attached to the skin for long-term colorimetric indicating. The design of color-changing silk fibroin film presented here provides a new direction of thinking for the preparation of substrate materials for stimulation-responsive biosensors. Smart color-changing films are emerging as promising functional materials having multiple applications. pH-responsive discoloration film can present optical response to outer pH value, which has diverse functions like indicating, packaging and monitoring, etc. Prodigiosin possesses not only pH-responsive discoloration property but biodegradability and biocompatibility. Based on these properties, an effective approach to develop pH-responsive discoloration film with biodegradability is proposed. Prodigiosins from microbial fermentation were evenly dispersed in silk fibroin solution to form a well-developed composite film via the casting method, exhibiting switchable pH-responsive color-changing performance. The film showed reddish-purple (λ max = 535 nm) at pH below 8, and turned orange and yellow (λ max = 480 nm) as the pH increased from 8 to 10. The glycerol and 1-(3-Dimethylaminopropyl)-3-ethyl carbodiimide hydro (EDC) were incorporated as plasticizing and cross-linking agents, respectively. Glycerol and EDC significantly reduced the water contact angle from 83.4° to 4.7°and improved the mechanical properties of pH-responsive silk fibroin film. In addition, this pH-responsive silk fibroin-based film is biodegradable and can be attached to the skin for long-term colorimetric indicating. The design of color-changing silk fibroin film presented here provides a new direction of thinking for the preparation of substrate materials for stimulation-responsive biosensors.
智能变色薄膜是一种具有多种用途的功能材料。pH响应变色膜能对外界pH值产生光学响应，具有指示、包装、监测等多种功能。子红素是一种主要来源于微生物次生代谢产物的天然红色素，具有生物可降解性和生物相容性。基于这些特性，提出了一种开发具有生物降解性的ph响应变色膜的有效方法。将微生物发酵产生的菌红素均匀分散在丝素溶液中，通过浇铸法形成发育良好的复合膜，具有可切换的ph响应变色性能。当pH值低于8时，膜呈红紫色(λ max = 530 nm)，当pH值从8增加到10时，膜变为橙色和黄色(λ max = 480 nm)。将甘油和1-(3-二甲氨基丙基)-3-乙基碳二亚胺氢(EDC)分别作为增塑剂和交联剂。甘油和EDC显著降低了水接触角，从83.4°降低到4.7°，提高了ph响应丝素膜的力学性能。此外，这种基于丝素蛋白的ph响应膜是可生物降解的，可以附着在皮肤上进行长期的比色指示。本文提出的变色丝素膜的设计为刺激响应型生物传感器基底材料的制备提供了新的思路。智能变色薄膜是一种具有多种用途的功能材料。pH响应变色膜能对外界pH值产生光学响应，具有指示、包装、监测等多种功能。菌红素不仅具有ph响应变色特性，而且具有生物降解性和生物相容性。基于这些特性，提出了一种开发具有生物降解性的ph响应变色膜的有效方法。将微生物发酵产生的菌红素均匀分散在丝素溶液中，通过浇铸法形成发育良好的复合膜，具有可切换的ph响应变色性能。当pH值低于8时，膜呈红紫色(λ max = 535 nm)，当pH值从8增加到10时，膜呈橙色和黄色(λ max = 480 nm)。将甘油和1-(3-二甲氨基丙基)-3-乙基碳二亚胺氢(EDC)分别作为增塑剂和交联剂。甘油和EDC显著降低了水接触角，从83.4°降低到4.7°，提高了ph响应丝素膜的力学性能。此外，这种基于丝素蛋白的ph响应膜是可生物降解的，可以附着在皮肤上进行长期的比色指示。本文提出的变色丝素膜的设计为刺激响应型生物传感器基底材料的制备提供了新的思路。
期刊介绍：
Dyes and Pigments covers the scientific and technical aspects of the chemistry and physics of dyes, pigments and their intermediates. Emphasis is placed on the properties of the colouring matters themselves rather than on their applications or the system in which they may be applied.
Thus the journal accepts research and review papers on the synthesis of dyes, pigments and intermediates, their physical or chemical properties, e.g. spectroscopic, surface, solution or solid state characteristics, the physical aspects of their preparation, e.g. precipitation, nucleation and growth, crystal formation, liquid crystalline characteristics, their photochemical, ecological or biological properties and the relationship between colour and chemical constitution. However, papers are considered which deal with the more fundamental aspects of colourant application and of the interactions of colourants with substrates or media.
The journal will interest a wide variety of workers in a range of disciplines whose work involves dyes, pigments and their intermediates, and provides a platform for investigators with common interests but diverse fields of activity such as cosmetics, reprographics, dye and pigment synthesis, medical research, polymers, etc.
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